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Details

Stereochemistry ACHIRAL
Molecular Formula C15H24N2O2.H3O4P
Molecular Weight 362.3584
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIMETHOLIZINE PHOSPHATE

SMILES

OP(O)(O)=O.COCCCN1CCN(CC1)C2=CC=CC=C2OC

InChI

InChIKey=NCOMQNWYMLGJPF-UHFFFAOYSA-N
InChI=1S/C15H24N2O2.H3O4P/c1-18-13-5-8-16-9-11-17(12-10-16)14-6-3-4-7-15(14)19-2;1-5(2,3)4/h3-4,6-7H,5,8-13H2,1-2H3;(H3,1,2,3,4)

HIDE SMILES / InChI
Molecular Formula H3O4P
Molecular Weight 97.9952
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C15H24N2O2
Molecular Weight 264.3633
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Dimetholizine has antihypertensive activity. It is an antihistaminic agent too. Histamine H1 receptor was predicted as a primary target for dimetholizine. Moreover, it was found to bind the Dopamine D2 and 5-HT1A receptors. Dimetholizine was predicted to be alpha1D-Adrenergic blocker.

Approval Year

Unknown
139594
Patents

Patents

20100226943
185
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:35:34 GMT 2023
Edited
by admin
on Sat Dec 16 01:35:34 GMT 2023
Record UNII
8VNU0OD47W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIMETHOLIZINE PHOSPHATE
Common Name English
PIPERAZINE, 1-(2-METHOXYPHENYL)-4-(3-METHOXYPROPYL)-, PHOSPHATE
Systematic Name English
ANSIV
Brand Name English
PIPERAZINE, 1-(O-METHOXYPHENYL)-4-(3-METHOXYPROPYL)-, PHOSPHATE
Common Name English
Code System Code Type Description
PUBCHEM
71586971
Created by admin on Sat Dec 16 01:35:34 GMT 2023 , Edited by admin on Sat Dec 16 01:35:34 GMT 2023
PRIMARY
CAS
13980-98-8
Created by admin on Sat Dec 16 01:35:34 GMT 2023 , Edited by admin on Sat Dec 16 01:35:34 GMT 2023
PRIMARY
EPA CompTox
DTXSID70161172
Created by admin on Sat Dec 16 01:35:34 GMT 2023 , Edited by admin on Sat Dec 16 01:35:34 GMT 2023
PRIMARY
FDA UNII
8VNU0OD47W
Created by admin on Sat Dec 16 01:35:34 GMT 2023 , Edited by admin on Sat Dec 16 01:35:34 GMT 2023
PRIMARY
Related Record Type Details
Structure of DIMETHOLIZINE
PARENT -> SALT/SOLVATE
NIH
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