ST-1535

CCCCC1=NC(N)=C2N=C(N(C)C2=N1)N3N=CC=N3

InChIKey=CYYQMAWUIRPCNW-UHFFFAOYSA-N

InChI=1S/C12H16N8/c1-3-4-5-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-6-7-15-20/h6-7H,3-5H2,1-2H3,(H2,13,16,17)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Interaction of A2A adenosine and D2 dopamine receptors modulates corticostriatal glutamatergic transmission.	2007 Nov	17889039
Behavioural and neurochemical characterization of the adenosine A2A receptor antagonist ST1535.	2008 Jan 28	18036583
Direct B-alkyl Suzuki-Miyaura cross-coupling of 2-halopurines. Practical synthesis of ST1535, a potent adenosine A2A receptor antagonist.	2010 Aug 6	20597521

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:32:30 GMT 2023` Edited by `admin` on `Sat Dec 16 15:32:30 GMT 2023`
Record UNII	NTK8WWM73W
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ST-1535

Code

English

CT-1500

Code

English

2-butyl-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-6-amine

Systematic Name

English

2-Butyl-9-methyl-8-(triazol-2-yl)purin-6-amine

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

811021