U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C26H26I6N2O10
Molecular Weight 1287.9189
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IODOXAMIC ACID

SMILES

OC(=O)C1=C(I)C=C(I)C(NC(=O)CCOCCOCCOCCOCCC(=O)NC2=C(I)C=C(I)C(C(O)=O)=C2I)=C1I

InChI

InChIKey=WWVAPFRKZMUPHZ-UHFFFAOYSA-N
InChI=1S/C26H26I6N2O10/c27-13-11-15(29)23(21(31)19(13)25(37)38)33-17(35)1-3-41-5-7-43-9-10-44-8-6-42-4-2-18(36)34-24-16(30)12-14(28)20(22(24)32)26(39)40/h11-12H,1-10H2,(H,33,35)(H,34,36)(H,37,38)(H,39,40)

HIDE SMILES / InChI

Molecular Formula C26H26I6N2O10
Molecular Weight 1287.9189
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Iodoxamic acid (previously sold under the brand name Cholovue) is an organoiodine compound that was used as a contrast medium. It is intravenous cholecystocholangiographic agent. It features both a high iodine content as well as several hydrophilic groups.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
CHOLOVUE

Approved Use

Contrast medium for biliary-tract radiography
PubMed

PubMed

TitleDatePubMed
A new contrast medium for cholangio-cholecystography: meglumine iodoxamete.
1975 Sep
Double-blind comparison of meglumine lodoxamate (Cholovue) and meglumine iodipamide (Cholografin).
1976 Aug
Intravenous cholangiography by bolus injection of meglumine iotroxamate and meglumine iodoxamate: a comparative trial of two new contrast media.
1981 Jul
Patents

Sample Use Guides

In Vivo Use Guide
A total of 90 patients were given an intravenous injection of 20 ml of 40% meglumine iodoxamate (iodoxamic acid) containing 183 mg/mI of organically bound iodine. The 20 ml dose was given intravenously over a 10 mm interval.
Route of Administration: Intravenous
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:04:05 GMT 2023
Edited
by admin
on Fri Dec 15 15:04:05 GMT 2023
Record UNII
NS1Y283HW4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IODOXAMIC ACID
II   INN   JAN   MART.   USAN   WHO-DD  
USAN   INN  
Official Name English
ENDOMIRABIL
Brand Name English
B-10610
Code English
3,3'-(ETHYLENEBIS(OXYETHYLENEOXYETHYLENECARBONYLIMINO))BIS(2,4,6-TRIIODOBENZOIC ACID)
Systematic Name English
iodoxamic acid [INN]
Common Name English
ENDOBIL
Brand Name English
IODOXAMIC ACID [USAN]
Common Name English
B 10610
Code English
IODOXAMIC ACID [II]
Common Name English
SQ-21982
Code English
VIDEOCOLANGIO
Brand Name English
SQ 21982
Code English
IODOXAMIC ACID [MART.]
Common Name English
Iodoxamic acid [WHO-DD]
Common Name English
IODOXAMIC ACID [JAN]
Common Name English
BENZOIC ACID, 3,3'-((1,16-DIOXO-4,7,10,13-TETRAOXAHEXADECANE-1,16-DIYL)DIIMINO)BIS(2,4,6-TRIIODO-
Systematic Name English
IODOXAMID
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C28500
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
WHO-VATC QV08AC01
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
WHO-ATC V08AC01
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
Code System Code Type Description
DRUG BANK
DB13539
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
MESH
C100278
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
ECHA (EC/EINECS)
250-478-1
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
EVMPD
SUB08218MIG
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
ChEMBL
CHEMBL1615487
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
DRUG CENTRAL
3966
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
CAS
31127-82-9
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
FDA UNII
NS1Y283HW4
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
INN
3095
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
PUBCHEM
35740
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
SMS_ID
100000083632
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
RXCUI
51471
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY RxNorm
WIKIPEDIA
Iodoxamic acid
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
NCI_THESAURUS
C65936
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
EPA CompTox
DTXSID4057710
Created by admin on Fri Dec 15 15:04:06 GMT 2023 , Edited by admin on Fri Dec 15 15:04:06 GMT 2023
PRIMARY
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