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Details

Stereochemistry ACHIRAL
Molecular Formula C21H19F2N3O3
Molecular Weight 399.3915
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RWJ-51204

SMILES

CCOCN1c2cc(ccc2N3CCC(=O)C(=C31)C(=Nc4ccccc4F)O)F

InChI

InChIKey=VQOQDABVGWLROX-UHFFFAOYSA-N
InChI=1S/C21H19F2N3O3/c1-2-29-12-26-17-11-13(22)7-8-16(17)25-10-9-18(27)19(21(25)26)20(28)24-15-6-4-3-5-14(15)23/h3-8,11H,2,9-10,12H2,1H3,(H,24,28)

HIDE SMILES / InChI

Molecular Formula C21H19F2N3O3
Molecular Weight 399.3915
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Sat Jun 26 01:26:06 UTC 2021
Edited
by admin
on Sat Jun 26 01:26:06 UTC 2021
Record UNII
NNJ1LL72JS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RWJ-51204
Common Name English
5-(ETHOXYMETHYL)-7-FLUORO-N-(2-FLUOROPHENYL)-1,2,3,5-TETRAHYDRO-3-OXOPYRIDO(1,2A)BENZIMIDAZOLE-4-CARBOXAMIDE
Systematic Name English
PYRIDO(1,2-A)BENZIMIDAZOLE-4-CARBOXAMIDE, 5-(ETHOXYMETHYL)-7-FLUORO-N-(2-FLUOROPHENYL)-1,2,3,5-TETRAHYDRO-3-OXO-
Systematic Name English
5-(ETHOXYMETHYL)-7-FLUORO-N-(2-FLUOROPHENYL)-3-OXO-1,2-DIHYDROPYRIDO(1,2-A)BENZIMIDAZOLE-4-CARBOXAMIDE
Systematic Name English
RWJ 51204
Code English
Code System Code Type Description
FDA UNII
NNJ1LL72JS
Created by admin on Sat Jun 26 01:26:06 UTC 2021 , Edited by admin on Sat Jun 26 01:26:06 UTC 2021
PRIMARY
CAS
205701-85-5
Created by admin on Sat Jun 26 01:26:06 UTC 2021 , Edited by admin on Sat Jun 26 01:26:06 UTC 2021
PRIMARY
PUBCHEM
9822240
Created by admin on Sat Jun 26 01:26:06 UTC 2021 , Edited by admin on Sat Jun 26 01:26:06 UTC 2021
PRIMARY
WIKIPEDIA
RWJ-51204
Created by admin on Sat Jun 26 01:26:06 UTC 2021 , Edited by admin on Sat Jun 26 01:26:06 UTC 2021
PRIMARY RWJ-51204 is an anxiolytic drug used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. RWJ-51204 is a nonselective partial agonist at GABAA receptors. It produces primarily anxiolytic effects at low doses, with sedative, ataxia and muscle relaxant effects only appearing at some 20x the effective anxiolytic dose.(2) It was discovered by researchers at the pharmaceutical company Johnson & Johnson, but its development has been discontinued.
Related Record Type Details
TARGET->PARTIAL AGONIST
Related Record Type Details
ACTIVE MOIETY