Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | As |
| Molecular Weight | 74.9216 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[As]
InChI
InChIKey=RBFQJDQYXXHULB-UHFFFAOYSA-N
InChI=1S/AsH3/h1H3
| Molecular Formula | As |
| Molecular Weight | 74.9216 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of arsenic exposure and genetic polymorphisms of p53, glutathione S-transferase M1, T1, and P1 on the risk of carotid atherosclerosis in Taiwan. | 2007-06 |
|
| Polymorphism in the ERCC2 codon 751 is associated with arsenic-induced premalignant hyperkeratosis and significant chromosome aberrations. | 2007-03 |
|
| Role of glucocorticoid receptor in acclimation of killifish (Fundulus heteroclitus) to seawater and effects of arsenic. | 2007-02 |
|
| Induction of oxidative stress by arsenic in Clarias batrachus: involvement of peroxisomes. | 2007-02 |
|
| Increased glycophorin A somatic cell variant frequency in arsenic-exposed patients of Guizhou, China. | 2006-11-01 |
|
| Plasma-transforming growth factor-alpha expression in residents of an arseniasis area in Taiwan. | 2006-10-24 |
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| Association of specific p53 polymorphisms with keratosis in individuals exposed to arsenic through drinking water in West Bengal, India. | 2006-10-10 |
|
| Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-associated carotid atherosclerosis. | 2006-10-01 |
|
| Does arsenic exposure increase the risk of development of peripheral vascular diseases in humans? | 2006-10 |
|
| Enhanced expression of metallothionein isoform 3 protein in tumor heterotransplants derived from As+3- and Cd+2-transformed human urothelial cells. | 2006-10 |
|
| Arsenic binding to human metallothionein. | 2006-09-27 |
|
| Blood arsenic as a biomarker of arsenic exposure: results from a prospective study. | 2006-08-15 |
|
| Arsenite pretreatment enhances the cytotoxicity of mitomycin C in human cancer cell lines via increased NAD(P)H quinone oxidoreductase 1 expression. | 2006-08-01 |
|
| Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. | 2006-08 |
|
| shRNA silencing of AS3MT expression minimizes arsenic methylation capacity of HepG2 cells. | 2006-07 |
|
| Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. | 2006-07 |
|
| Modification of risk of arsenic-induced skin lesions by sunlight exposure, smoking, and occupational exposures in Bangladesh. | 2006-07 |
|
| Glutathione S-transferase omega 1 and omega 2 pharmacogenomics. | 2006-07 |
|
| Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. | 2006-07 |
|
| [Mechanism of tetra-arsenic tetra-sulfide in inducing apoptosis of acute promyelocytic leukemia cells]. | 2006-06-18 |
|
| Arsenic exposure from drinking water and risk of premalignant skin lesions in Bangladesh: baseline results from the Health Effects of Arsenic Longitudinal Study. | 2006-06-15 |
|
| Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes. | 2006-06-15 |
|
| Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver. | 2006-06-15 |
|
| Chronic arsenic exposure and oxidative stress: OGG1 expression and arsenic exposure, nail selenium, and skin hyperkeratosis in Inner Mongolia. | 2006-06 |
|
| Cytogenetic damage and genetic variants in the individuals susceptible to arsenic-induced cancer through drinking water. | 2006-05-15 |
|
| Gender-specific protective effect of hemoglobin on arsenic-induced skin lesions. | 2006-05 |
|
| Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies. | 2006-03-17 |
|
| Global gene expression associated with hepatocarcinogenesis in adult male mice induced by in utero arsenic exposure. | 2006-03 |
|
| The impact of diet and betel nut use on skin lesions associated with drinking-water arsenic in Pabna, Bangladesh. | 2006-03 |
|
| Prevalence of arsenic exposure and skin lesions. A population based survey in Matlab, Bangladesh. | 2006-03 |
|
| Defective beta1-integrins expression in arsenical keratosis and arsenic-treated cultured human keratinocytes. | 2006-02 |
|
| DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy. | 2006-02 |
|
| Carcinogen exposure and gene promoter hypermethylation in bladder cancer. | 2006-01 |
|
| Mytilus trossulus hsp70 as a biomarker for arsenic exposure in the marine environment: laboratory and real-world results. | 2005-11-26 |
|
| Effects of glutamine on adhesion molecule expression and leukocyte transmigration in endothelial cells exposed to arsenic. | 2005-11 |
|
| A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh. | 2005-10 |
|
| Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water. | 2005-10 |
|
| Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats. | 2005-09-16 |
|
| Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase. | 2005-09-01 |
|
| Acquisition of androgen independence by human prostate epithelial cells during arsenic-induced malignant transformation. | 2005-09 |
|
| Genetic polymorphisms of oxidative and antioxidant enzymes and arsenic-related hypertension. | 2005-09 |
|
| Arsenic exposure, urinary arsenic speciation, and peripheral vascular disease in blackfoot disease-hyperendemic villages in Taiwan. | 2005-08-15 |
|
| Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan. | 2005-08-07 |
|
| Association between arsenic exposure and a measure of subclinical sensory neuropathy in Bangladesh. | 2005-08 |
|
| Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children. | 2005-06 |
|
| GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy. | 2005-06 |
|
| Ligand arsenic complexation and immunoperoxidase detection of metallothionein in the earthworm Lumbricus rubellus inhabiting arsenic-rich soil. | 2005-04-01 |
|
| [Study on the relationship between methylene tetrahydrofolate reductase gene (677C-->T) mutation and skin lesions in endemic arsenic poisoning]. | 2005-03 |
|
| Functional characteristics of NaS2, a placenta-specific Na+-coupled transporter for sulfate and oxyanions of the micronutrients selenium and chromium. | 2005-01-25 |
|
| Modulation of murine peritoneal macrophage function by chronic exposure to arsenate in drinking water. | 2005 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:31:20 GMT 2025
by
admin
on
Mon Mar 31 18:31:20 GMT 2025
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| Record UNII |
N712M78A8G
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| Record Status |
Validated (UNII)
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| Record Version |
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FDA ORPHAN DRUG |
146001
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CFR |
21 CFR 862.3120
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NCI_THESAURUS |
C1940
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| Code System | Code | Type | Description | ||
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m2054
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PRIMARY | Merck Index | ||
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D001151
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1111
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27563
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DTXSID4023886
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N712M78A8G
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100000088016
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N712M78A8G
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C28131
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176584
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5359596
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Arsenic
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231-148-6
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SUB23558
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509
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7440-38-2
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> CONSTITUENT ALWAYS PRESENT |
ARSENIC (ng/cigarette)
Canadian = 151.4 SD(64.4)
Imported = 169.2 (26.2)
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> IMPURITY |
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PARENT -> IMPURITY |
EP
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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