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Details

Stereochemistry ACHIRAL
Molecular Formula C14H16N4O3
Molecular Weight 288.3018
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 2

SHOW SMILES / InChI
Structure of OBIDOXIME

SMILES

O\N=C\C1=CC=[N+](COC[N+]2=CC=C(C=C2)\C=N\O)C=C1

InChI

InChIKey=HIGRLDNHDGYWQJ-UHFFFAOYSA-P
InChI=1S/C14H14N4O3/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20/h1-10H,11-12H2/p+2

HIDE SMILES / InChI

Molecular Formula C14H14N4O3
Molecular Weight 286.286
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Obidoxime is an antidote for organophosphorous nerve agent poisoning including chlorosarin, cyclosarin (GF), R-33 (VR), R-VX, sarin (GB), tabun (GA), VX, chlorosoman, soman (GD), and organophosphorous pesticides. It acts as an acetylcholinesterase (AChE) reactivator. In combination with atropine obidoxime can be used to treat super toxic organophosphate poisoning by relieving the symptoms of skeletal neuromuscular blocking that occurs during a cholinergic crisis.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
Substance Class Chemical
Record UNII
N6KNE1QA9O
Record Status Validated (UNII)
Record Version