SEPERIDOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H22ClF4NO2
Molecular Weight	443.862
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C(=C3)C(F)(F)F

InChI

InChIKey=LZFSKNPPWIFMFL-UHFFFAOYSA-N

InChI=1S/C22H22ClF4NO2/c23-19-8-5-16(14-18(19)22(25,26)27)21(30)9-12-28(13-10-21)11-1-2-20(29)15-3-6-17(24)7-4-15/h3-8,14,30H,1-2,9-13H2

HIDE SMILES / InChI

Molecular Formula	C22H22ClF4NO2
Molecular Weight	443.862
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4972601 | https://www.genome.jp/dbget-bin/www_bget?D02685

Seperidol (also known as clofluperol or R9298), a butyrophenone derivative that was developed as an antipsychotic agent. This compound was studied as a long-acting neuroleptic. However, information about the current use of seperidol is not available.

Approval Year

PubMed

Title	Date	PubMed
[Long-acting neuroleptics. I. Pilot study of clofluperol (R9298)].	1968 Feb	4972601
The distribution of the butyrophenones haloperidol, trifluperidol, moperone, and clofluperol in rats, and its relationship with their neuroleptic activity.	1969 Feb	5818759
Development of tolerance to the stimulatory effect of neuroleptic butyrophenones on pituitary-adrenal activity in rats.	1981 Nov	6120222

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:57 GMT 2023` Edited by `admin` on `Fri Dec 15 15:16:57 GMT 2023`
Record UNII	N57F04DIDQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SEPERIDOL

Common Name

English

clofluperol [INN]

Common Name

English

CLOFLUPEROL

Official Name

English

1-BUTANONE, 4-(4-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)-4-HYDROXY-1-PIPERIDINYL)-1-(4-FLUOROPHENYL)-

Systematic Name

English

Code System Code Type Description

CAS

10457-91-7