SEPERIDOL HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H22ClF4NO2.ClH
Molecular Weight	480.323
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C(=C3)C(F)(F)F

InChI

InChIKey=MNEIBEWKVRSDEX-UHFFFAOYSA-N

InChI=1S/C22H22ClF4NO2.ClH/c23-19-8-5-16(14-18(19)22(25,26)27)21(30)9-12-28(13-10-21)11-1-2-20(29)15-3-6-17(24)7-4-15;/h3-8,14,30H,1-2,9-13H2;1H

HIDE SMILES / InChI

Molecular Formula	C22H22ClF4NO2
Molecular Weight	443.862
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4972601 | https://www.genome.jp/dbget-bin/www_bget?D02685

Seperidol (also known as clofluperol or R9298), a butyrophenone derivative that was developed as an antipsychotic agent. This compound was studied as a long-acting neuroleptic. However, information about the current use of seperidol is not available.

Approval Year

PubMed

Title	Date	PubMed
[Long-acting neuroleptics. I. Pilot study of clofluperol (R9298)].	1968 Feb	4972601
The distribution of the butyrophenones haloperidol, trifluperidol, moperone, and clofluperol in rats, and its relationship with their neuroleptic activity.	1969 Feb	5818759
Effects of neuroleptic butyrophenones on pituitary-adrenal activity in rats.	1980 Jan	6110713

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:01:05 UTC 2023` Edited by `admin` on `Fri Dec 15 15:01:05 UTC 2023`
Record UNII	JA0GE6S29W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SEPERIDOL HYDROCHLORIDE

Official Name

English

SPERIDOL HYDROCHLORIDE

Common Name

English

1-BUTANONE, 4-(4-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)-4-HYDROXY-1-PIPERIDINYL)-1-(4-FLUOROPHENYL)-, HYDROCHLORIDE

Systematic Name

English

CLOFLUPEROL HYDROCHLORIDE

Common Name

English

R 9298

Code

English

SEPERIDOL HYDROCHLORIDE [USAN]

Common Name

English

R-9298

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29710