| Stereochemistry | UNKNOWN |
| Molecular Formula | C18H24I3N3O9 |
| Molecular Weight | 807.1113 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 0 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OCCN(C(=O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I
InChI
InChIKey=AMDBBAQNWSUWGN-UHFFFAOYSA-N
InChI=1S/C18H24I3N3O9/c19-13-11(17(32)22-3-8(29)5-26)14(20)16(24(1-2-25)10(31)7-28)15(21)12(13)18(33)23-4-9(30)6-27/h8-9,25-30H,1-7H2,(H,22,32)(H,23,33)
| Molecular Formula | C18H24I3N3O9 |
| Molecular Weight | 807.1113 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | MIXED |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Ioversol is an organoiodine compound that used as a contrast medium. It features both a high iodine content, as well as several hydrophilic groups. It is indicated in adults for peripheral and coronary arteriography and left ventriculography, for excretory urography and computed tomography. Injections of contrast media are often associated with sensations of warmth and pain. Renal toxicity has been reported in a few patients with liver dysfunction who were given oral cholecystographic agents followed by intravascular contrast agents.
CNS Activity
Originator
Approval Year
Doses
AEs
Overview
| CYP3A4 | CYP2C9 | CYP2D6 | hERG |
|---|---|---|---|
OverviewOther
| Other Inhibitor | Other Substrate | Other Inducer |
|---|---|---|
Drug as victim
Sourcing
PubMed
Patents
Sample Use Guides
Optiray (ioversol injection) 240, Optiray 300 or Optiray 320 is recommended for cerebral arteriography. The usual individual injection for visualization of the carotid or vertebral arteries is 2 to 12 mL. Aortic arch injection for a simultaneous four vessel study requires 20 to 50 mL. Total procedural doses should not usually exceed 200 mL. Optiray 300, Optiray 320 or Optiray 350 is recommended for peripheral arteriography. The dosage is 20-60 ml. Optiray 320 or Optiray 350 is recommended for coronary arteriography. The dosage is 6-40 mL. Optiray 320 is recommended for visceral arteriography, renal arteriography, and aortography procedures. The dosage is 9-45 mL. Optiray 240, Optiray 300, Optiray 320 or Optiray 350 is recommended for venography. The usual dose is 50 to 100 mL per extremity with smaller or larger volumes indicated in some cases. Dosage should not usually exceed 250 mL.
Route of Administration:
Intravascular
![Structure of N,N'-Bis(2,3-dihydroxypropyl)-5-{[N-(2-hydroxyethyl)amino]-2-oxoethoxy}-2,4,6-triiodoisophthalamide](/img/564d3d14-5556-4579-8efb-53b029322ed6.svg "Structure of N,N'-Bis(2,3-dihydroxypropyl)-5-{[N-(2-hydroxyethyl)amino]-2-oxoethoxy}-2,4,6-triiodoisophthalamide")
