SULFATHIOUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9N3O2S2
Molecular Weight	231.295
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=S)NS(=O)(=O)C1=CC=C(N)C=C1

InChI

InChIKey=UEMLYRZWLVXWRU-UHFFFAOYSA-N

InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)

HIDE SMILES / InChI

Molecular Formula	C7H9N3O2S2
Molecular Weight	231.295
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.ncbi.nlm.nih.gov/pubmed/21024878
Curator's Comment: description was created based on several sources, including http://www.ncbi.nlm.nih.gov/pubmed/13137202

Sulphathiourea (Badional) is short acting sulfonamide, belongs to antibacterial drugs

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections 234 Sources: http://drugs-about.com/ing/sulfathiourea.html	Curative		Approved 8429	Badional Approved Use Unknown

PubMed

Title	Date	PubMed
Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs.	1995 Aug	7486915
Possible association between different congenital abnormalities and use of different sulfonamides during pregnancy.	2004 Jun	15198720

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

In Vitro Use Guide

Tests of capacity to inhibit growth showed sulphathiourea to be inferior to sulphadimetine for most Gram-negative organisms except Shigella, but superior to it in its action on Gram-positive organisms, notably haemolytic streptococci and staphylococci. Sulphathiourea is bactericidal when added to a culture in the early stages of growth

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:51:05 GMT 2023` Edited by `admin` on `Fri Dec 15 15:51:05 GMT 2023`
Record UNII	MXF9G4I1V5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFATHIOUREA

Official Name

English

Sulfathiourea [WHO-DD]

Common Name

English

SULFATHIOUREA [MI]

Common Name

English

sulfathiourea [INN]

Common Name

English

NSC-108228

Code

English

Classification Tree Code System Code

WHO-ATC

J01EB08