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Details

Stereochemistry ACHIRAL
Molecular Formula C7H10N2O2S.C7H9N3O2S2
Molecular Weight 417.527
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFATOLAMIDE

SMILES

NCC1=CC=C(C=C1)S(N)(=O)=O.NC(=S)NS(=O)(=O)C2=CC=C(N)C=C2

InChI

InChIKey=ZLYHTQKHXIVMLY-UHFFFAOYSA-N
InChI=1S/C7H9N3O2S2.C7H10N2O2S/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13;8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,8H2,(H3,9,10,13);1-4H,5,8H2,(H2,9,10,11)

HIDE SMILES / InChI
Molecular Formula C7H9N3O2S2
Molecular Weight 231.295
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C7H10N2O2S
Molecular Weight 186.231
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Sulfatolamide is a combination of two sulfonamide antibacterials, sulfathiourea and mafenide, previously used in the treatment of gynecological infections.

Originator

Hartmann
1

Approval Year

Unknown
139,594

Conditions

ConditionModalityTargetsHighest PhaseProduct
Genital infections
3
 Curative
Approved
8,429
Marbadal

PubMed

Patents

CA2767044C
1
EP2273989A1
1
US20060269485
2
US9211259
1

Sample Use Guides

In Vivo Use Guide
vaginal tablets
Route of Administration: Vaginal
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
3OLH2HAK9F
Record Status Validated (UNII)
Record Version
NIH
NCATS
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