SULFATOLAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H10N2O2S.C7H9N3O2S2
Molecular Weight	417.527
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NCC1=CC=C(C=C1)S(N)(=O)=O.NC(=S)NS(=O)(=O)C2=CC=C(N)C=C2

InChI

InChIKey=ZLYHTQKHXIVMLY-UHFFFAOYSA-N

InChI=1S/C7H9N3O2S2.C7H10N2O2S/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13;8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,8H2,(H3,9,10,13);1-4H,5,8H2,(H2,9,10,11)

HIDE SMILES / InChI

Molecular Formula	C7H9N3O2S2
Molecular Weight	231.295
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C7H10N2O2S
Molecular Weight	186.231
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C76983 | https://www.ncbi.nlm.nih.gov/pubmed/14890519

Sulfatolamide is a combination of two sulfonamide antibacterials, sulfathiourea and mafenide, previously used in the treatment of gynecological infections.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Genital infections 3 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15426235 https://www.ncbi.nlm.nih.gov/pubmed/14890519 http://www.bmj.com/content/1/5230/968.2 https://www.ncbi.nlm.nih.gov/pubmed/14867681	Curative		Approved 8429	Marbadal Approved Use Genital infections

PubMed

Title	Date	PubMed
[Results of capillary fragilometry, and changes in blood coagulation after intraperitoneal instillation and marbadal].	1954	13189420
[The intraperitoneal use of marbadal as possible cause of thrombosis].	1954 Jul 30	13200195
[Reaction products in the determination of the constituents of marbadal].	1956 Jan	13328049

Patents

Sample Use Guides

In Vivo Use Guide

vaginal tablets

Route of Administration: Vaginal

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:20:10 GMT 2023` Edited by `admin` on `Sat Dec 16 16:20:10 GMT 2023`
Record UNII	3OLH2HAK9F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFATOLAMIDE

Official Name

English

SULFATOLAMIDE [MI]

Common Name

English

sulfatolamide [INN]

Common Name

English

SULFATOLAMIDE [MART.]

Common Name

English

Sulfatolamide [WHO-DD]

Common Name

English

SULFATOLAMIDE [JAN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

G01AE01