ELANTRINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H24N2
Molecular Weight	292.418
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CCC=C1C2=CC=CC=C2CN(C)C3=CC=CC=C13

InChI

InChIKey=YFFIQHDMUUCCJP-UHFFFAOYSA-N

InChI=1S/C20H24N2/c1-21(2)14-8-12-18-17-10-5-4-9-16(17)15-22(3)20-13-7-6-11-19(18)20/h4-7,9-13H,8,14-15H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C20H24N2
Molecular Weight	292.418
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/337773 | https://www.ncbi.nlm.nih.gov/pubmed/798127

Elantrine is an anticholinergic drug. Elantrine has been investigated in the treatment of parkinsonism.

CNS Activity

Approval Year

PubMed

Title	Date	PubMed
Evaluation of an experimental anticholinergic drug, elantrine, in treating the tremor of parkinsonism.	1977	337773
Elantrine in the treatment of parkinsonism.	1976	798127
Phase II multiclinic study of elantrine in parkinsonism.	1974-01	4587106
The effect of elantrine, a new anti-Parkinsonism agent, on drug-induced tremor in mice.	1972-05	5031571

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:51:36 GMT 2025` Edited by `admin` on `Mon Mar 31 17:51:36 GMT 2025`
Record UNII	MV4FO7V23V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ELANTRINE

Official Name

English

NSC-172253

Preferred Name

English

11-[3-(Dimethylamino)propylidene]-5,6-dihydro-5-methylmorphanthridine

Common Name

English

RMI 80,029

Code

English

ELANTRINE [USAN]

Common Name

English

RMI-80029

Code

English

1-PROPANAMINE, 3-(5,6-DIHYDRO-5-METHYL-11H-DIBENZ(B,E)AZEPIN-11-YLIDENE-N,N-DIMETHYL-

Common Name

English

EX 10-029-C

Code

English

elantrine [INN]

Common Name

English

EX-10-029-C

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C66880