U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C20H24N2.2C6H13NO3S
Molecular Weight 650.893
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ELANTRINE DI(CYCLOHEXYLSULFAMATE)

SMILES

OS(=O)(=O)NC1CCCCC1.OS(=O)(=O)NC2CCCCC2.CN(C)CCC=C3C4=C(CN(C)C5=C3C=CC=C5)C=CC=C4

InChI

InChIKey=JOIRQFVXFYEKIL-UHFFFAOYSA-N
InChI=1S/C20H24N2.2C6H13NO3S/c1-21(2)14-8-12-18-17-10-5-4-9-16(17)15-22(3)20-13-7-6-11-19(18)20;2*8-11(9,10)7-6-4-2-1-3-5-6/h4-7,9-13H,8,14-15H2,1-3H3;2*6-7H,1-5H2,(H,8,9,10)

HIDE SMILES / InChI
Molecular Formula C20H24N2
Molecular Weight 292.418
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE
Molecular Formula C6H13NO3S
Molecular Weight 179.237
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Elantrine is an anticholinergic drug. Elantrine has been investigated in the treatment of parkinsonism.

CNS Activity

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
The effect of elantrine, a new anti-Parkinsonism agent, on drug-induced tremor in mice.
1972 May
Phase II multiclinic study of elantrine in parkinsonism.
1974 Jan
Elantrine in the treatment of parkinsonism.
1976
Evaluation of an experimental anticholinergic drug, elantrine, in treating the tremor of parkinsonism.
1977
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:00:19 GMT 2023
Edited
by admin
on Fri Dec 15 16:00:19 GMT 2023
Record UNII
UL30Q518N9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ELANTRINE DI(CYCLOHEXYLSULFAMATE)
Common Name English
5-METHYL-11-(3-DIMETHYLAMINOPROPYLIDENE)-5,6-DIHYDROMORPHANTHRIDINE DICYCLOHEXYLSULFAMATE
Common Name English
CYCLOHEXANESULFAMIC ACID, COMPD. WITH 11-(3-(DIMETHYLAMINO)PROPYLIDENE)-5,6-DIHYDRO-5-METHYLMORPHANTHRIDINE (2:1)
Common Name English
SULFAMIC ACID, N-CYCLOHEXYL-, COMPD. WITH 3-(5,6-DIHYDRO-5-METHYL-11H-DIBENZ(B,E)AZEPIN-11-YLIDENE)-N,N-DIMETHYL-1-PROPANAMINE (2:1)
Systematic Name English
1-PROPANAMINE, 3-(5,6-DIHYDRO-5-METHYL-11H-DIBENZ(B,E)AZEPIN-11-YLIDENE)-N,N-DIMETHYL-, BIS(CYCLOHEXYLSULFAMATE)
Common Name English
NSC-172252
Code English
11-(3-DIMETHYLAMINOPROPYLIDENE)-5-METHYL-5,6-DIHYDROMORPHANTHRIDINE BIS(CYCLOHEXYLSULFAMATE)
Common Name English
Code System Code Type Description
NSC
172252
Created by admin on Fri Dec 15 16:00:19 GMT 2023 , Edited by admin on Fri Dec 15 16:00:19 GMT 2023
PRIMARY
CAS
1443-91-0
Created by admin on Fri Dec 15 16:00:19 GMT 2023 , Edited by admin on Fri Dec 15 16:00:19 GMT 2023
PRIMARY
FDA UNII
UL30Q518N9
Created by admin on Fri Dec 15 16:00:19 GMT 2023 , Edited by admin on Fri Dec 15 16:00:19 GMT 2023
PRIMARY
PUBCHEM
131873784
Created by admin on Fri Dec 15 16:00:19 GMT 2023 , Edited by admin on Fri Dec 15 16:00:19 GMT 2023
PRIMARY
Related Record Type Details
Structure of ELANTRINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of ELANTRINE
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966