FLAVODILOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H23NO4
Molecular Weight	353.4116
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FLAVODILOL

Structure Search

SMILES

CCCNCC(O)COC1=CC2=C(C=C1)C(=O)C=C(O2)C3=CC=CC=C3

InChI

InChIKey=KRBRHCLLOOCWQF-UHFFFAOYSA-N

InChI=1S/C21H23NO4/c1-2-10-22-13-16(23)14-25-17-8-9-18-19(24)12-20(26-21(18)11-17)15-6-4-3-5-7-15/h3-9,11-12,16,22-23H,2,10,13-14H2,1H3

HIDE SMILES / InChI

Molecular Formula	C21H23NO4
Molecular Weight	353.4116
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2475704 | https://www.ncbi.nlm.nih.gov/pubmed/2475706

FLAVODILOL is an antihypertensive agent.

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor beta 87 Target ID: CHEMBL2095166 Sources: https://adisinsight.springer.com/drugs/800002394	Antagonist 2778		4.0 nM [Ki]

PubMed

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:53:11 GMT 2023` Edited by `admin` on `Sat Dec 16 17:53:11 GMT 2023`
Record UNII	M8FR1KL85J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FLAVODILOL

Official Name

English

(±)-7-(2-HYDROXY-3-(PROPYLAMINO)PROPOXY)FLAVONE

Systematic Name

English

flavodilol [INN]

Common Name

English

4H-1-BENZOPYRAN-4-ONE, 7-(2-HYDROXY-3-(PROPYLAMINO)PROPOXY)-2-PHENYL-, (±)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

Code System Code Type Description

EVMPD

SUB07634MIG

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

PRIMARY

FDA UNII

M8FR1KL85J

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

PRIMARY

NCI_THESAURUS

C72783

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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SMS_ID

100000080971

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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EPA CompTox

DTXSID90868530

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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CAS

79619-31-1

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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ChEMBL

CHEMBL57185

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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MESH

C058114

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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INN

5279

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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PUBCHEM

54410

Created by admin on Sat Dec 16 17:53:12 GMT 2023 , Edited by admin on Sat Dec 16 17:53:12 GMT 2023

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Related Record Type Details

2344162F67

FLAVODILOL, (S)-

ENANTIOMER -> RACEMATE


					Y0DFC0D3Q8

FLAVODILOL MALEATE

SALT/SOLVATE -> PARENT


					95H7GS64L5

FLAVODILOL, (R)-

ENANTIOMER -> RACEMATE

Related Record Type Details


					M8FR1KL85J

ACTIVE MOIETY