Details
Stereochemistry | UNKNOWN |
Molecular Formula | C12H18FNO |
Molecular Weight | 211.2758 |
Optical Activity | ( + ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(C)NCC(O)C1=C(F)C=CC=C1
InChI
InChIKey=XTJMTDZHCLBKFU-UHFFFAOYSA-N
InChI=1S/C12H18FNO/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13/h4-7,11,14-15H,8H2,1-3H3
Molecular Formula | C12H18FNO |
Molecular Weight | 211.2758 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1676181
Curator's Comment: Known to be CNS active in rat. Human data not available.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Effects of CRL 40827 and salbutamol on exocrine pancreatic secretion in rats. | 1988 Jan 27 |
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Flerobuterol, a beta-adrenoceptor agonist, enhances serotonergic neurotransmission: an electrophysiological study in the rat brain. | 1991 |
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Flerobuterol: a potential antidepressant drug related to beta-adrenergic agonists. Experimental profile in mice. | 1991 |
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Evidence for different interactions between beta(1)- and beta(2)-adrenoceptor subtypes with adenylyl cyclase in the rat brain: a concentration-response study using forskolin. | 2000 Apr |
Patents
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1676181
Flerobuterol is a beta1- and beta2-adrenoceptor agonist (Ki = 926 nM and 518 nM, respectively).
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:31:24 GMT 2023
by
admin
on
Fri Dec 15 19:31:24 GMT 2023
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Record UNII |
M5Q6BN4795
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Record Status |
Validated (UNII)
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Record Version |
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101687-94-9
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M5Q6BN4795
Created by
admin on Fri Dec 15 19:31:24 GMT 2023 , Edited by admin on Fri Dec 15 19:31:24 GMT 2023
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Related Record | Type | Details | ||
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ENANTIOMER -> ENANTIOMER |
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RACEMATE -> ENANTIOMER |