PRENALTEROL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H19NO3
Molecular Weight	225.2842
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NC[C@H](O)COC1=CC=C(O)C=C1

InChI

InChIKey=ADUKCCWBEDSMEB-NSHDSACASA-N

InChI=1S/C12H19NO3/c1-9(2)13-7-11(15)8-16-12-5-3-10(14)4-6-12/h3-6,9,11,13-15H,7-8H2,1-2H3/t11-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C12H19NO3
Molecular Weight	225.2842
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7270401 | https://www.ncbi.nlm.nih.gov/pubmed/3191661 | https://www.ncbi.nlm.nih.gov/pubmed/2572262

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Beta-1 adrenergic receptor 158 Target ID: CHEMBL213 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1687080\|https://www.ncbi.nlm.nih.gov/pubmed/6131123\|https://www.ncbi.nlm.nih.gov/pubmed/6120845\|https://www.ncbi.nlm.nih.gov/pubmed/2564629	Partial Agonist 290		280.0 nM [Ki]

PubMed

Title	Date	PubMed
Noninvasive assessment of chronotropic and inotropic response to preferential beta-1 and beta-2 adrenoceptor stimulation.	1984 Jun	6145533
Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium.	1989 Mar	2564629
alpha- and beta-adrenergic receptor mechanisms in spontaneous contractile activity of rat ileal longitudinal smooth muscle.	2005 Feb	15694819
Role of selective alpha and beta adrenergic receptor mechanisms in rat jejunal longitudinal muscle contractility.	2008 Jun	17879122

Patents

Sample Use Guides

In Vivo Use Guide

The eight patients were given prenalterol (PNL) orally, 30 to 200 mg/day, versus placebo for 6 days

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:59:01 GMT 2023` Edited by `admin` on `Fri Dec 15 17:59:01 GMT 2023`
Record UNII	M4G34404CX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRENALTEROL

Official Name

English

prenalterol [INN]

Common Name

English

Prenalterol [WHO-DD]

Common Name

English

(-)-(S)-1-(P-HYDROXYPHENOXY)-3-(ISOPROPYLAMINO)-2-PROPANOL

Common Name

English

PRENALTEROL [MI]

Common Name

English

PHENOL, 4-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)-

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QC01CA13