Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H6NO.Na |
| Molecular Weight | 131.1077 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].NC1=CC=C([O-])C=C1
InChI
InChIKey=JMUGMTJKQOAQBS-UHFFFAOYSA-M
InChI=1S/C6H7NO.Na/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;/q;+1/p-1
| Molecular Formula | C6H6NO |
| Molecular Weight | 108.1179 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
p-Aminophenol is an active metabolite of paracetamol. p-Aminophenol is conjugated with arachidonic acid by fatty acid amide hydrolase to form AM404. AM404 exerts effect through cannabinoid receptors. p- Aminophenol is a nephrotoxic metabolite of paracetamol and phenacetin. It causes acute renal proximal tubular necrosis after administration to rats. p-Aminophenol may cause skin sensitization, dermatitis. p-Aminophenol is a synthetic dye used in hair coloring.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A new dynamic electrochemical transduction mechanism for interdigitated array microelectrodes. | 2004-12 |
|
| Degradation of 4-nitrophenol by the lignin-degrading basidiomycete Phanerochaete chrysosporium. | 2004-12 |
|
| Reactions of arylamine and aminophenol derivatives, and riboflavin with organic radicals. | 2004-11 |
|
| Toxic effects of aminophenols on aquatic life using the zebrafish embryo test and the comet assay. | 2004-10 |
|
| Microchip capillary electrophoresis with a boron-doped diamond electrochemical detector for analysis of aromatic amines. | 2004-09 |
|
| Pharmacophore based synthesis of 3-chloroquinoxaline-2-carboxamides as serotonin3 (5-HT3) receptor antagonist. | 2004-09 |
|
| Poly(dimethylsiloxane) microchip capillary electrophoresis with electrochemical detection for rapid measurement of acetaminophen and its hydrolysate. | 2004-08 |
|
| The measurement of alkaline phosphatase at nanomolar concentration within 70 s using a disposable microelectrochemical transistor. | 2004-08 |
|
| The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte concentration. | 2004-08 |
|
| Spectrophotometric determination of paracetamol with microwave assisted alkaline hydrolysis. | 2004-07 |
|
| Scanning electrochemical microscopy of quinoprotein glucose dehydrogenase. | 2004-06-01 |
|
| Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases. | 2004-06 |
|
| Bead-based immunoassays with microelectrode detection. | 2004-06 |
|
| Bead-based electrochemical immunoassay for bacteriophage MS2. | 2004-05-15 |
|
| Microbead-based electrochemical immunoassay with interdigitated array electrodes. | 2004-05-15 |
|
| Synthesis and biological activity of novel retinamide and retinoate derivatives. | 2004-05 |
|
| Hapten-directed targeting to single-chain antibody receptors. | 2004-05 |
|
| Toxicity and human health risk of hair dyes. | 2004-04 |
|
| Flow injection determination of p-aminophenol at trace level using inhibited luminol-dimethylsulfoxide-NaOH-EDTA chemiluminescence. | 2004-03-25 |
|
| Electrical detection of viral DNA using ultramicroelectrode arrays. | 2004-02-01 |
|
| Express detection of nonylphenol in water samples by fluorescence polarization immunoassay. | 2004-02 |
|
| Electric chips for rapid detection and quantification of nucleic acids. | 2004-01-15 |
|
| [Kinetics and mechanism of aniline oxidation with chlorine dioxide in water]. | 2004-01 |
|
| Effect of unlabeled helper probes on detection of an RNA target by bead-based sandwich hybridization. | 2004-01 |
|
| Automated spectrophotometric assay for urine p-aminophenol by an oxidative coupling reaction. | 2004 |
|
| Kinetics of aniline oxidation with chlorine dioxide. | 2004 |
|
| Toxicological detection of the new designer drug 1-(4-methoxyphenyl)piperazine and its metabolites in urine and differentiation from an intake of structurally related medicaments using gas chromatography-mass spectrometry. | 2003-12-25 |
|
| Oxidation-reduction potential as a control variable for the anaerobic stage during anaerobic-aerobic p-nitrophenol degradation. | 2003-12-06 |
|
| First enantiospecific total synthesis of the antitubercular marine natural product pseudopteroxazole. Revision of assigned stereochemistry. | 2003-11-05 |
|
| Enzyme-amplified electrochemical detection of DNA using electrocatalysis of ferrocenyl-tethered dendrimer. | 2003-11-01 |
|
| A potential biomarker of kidney damage identified by proteomics: preliminary findings. | 2003-08-29 |
|
| Determination of 4-aminophenol impurities in multicomponent analgesic preparations by HPLC with amperometric detection. | 2003-08-08 |
|
| Synthesis and activity of novel benzoxazole derivatives of mannopeptimycin glycopeptide antibiotics. | 2003-08-04 |
|
| Immobilized enzyme-linked DNA-hybridization assay with electrochemical detection for Cryptosporidium parvum hsp70 mRNA. | 2003-08-01 |
|
| Evolution of catabolic pathways for synthetic compounds: bacterial pathways for degradation of 2,4-dinitrotoluene and nitrobenzene. | 2003-08 |
|
| Enhancement of antioxidant activity of p-alkylaminophenols by alkyl chain elongation. | 2003-07-31 |
|
| Continuous biotransformation and removal of nitrophenols under denitrifying conditions. | 2003-07 |
|
| Validation of a method for quantification of ketobemidone in human plasma with liquid chromatography-tandem mass spectrometry. | 2003-06-15 |
|
| Unbiased spectrophotometric method for estimating phenol or o-cresol in unknown water samples. | 2003-06 |
|
| Generation of ligand conformations in continuum solvent consistent with protein active site topology: application to thrombin. | 2003-04-10 |
|
| Metalloantimalarials: targeting of P. falciparum strains with novel iron(III) and gallium(III) complexes of an amine phenol ligand. | 2003-04-07 |
|
| Sorption and diffusion of phenols onto well-defined ordered nanoporous monolithic silicas. | 2003-04-01 |
|
| The use of thermal lensing for the determination of pyrogens. | 2003-04 |
|
| Reversible and irreversible inhibitory activity of succinic and maleic acid derivatives on acetylcholinesterase. | 2003-04 |
|
| Dlf complexes with uniform coordination geometry: structural and magnetic properties of an LnNi2 core supported by a heptadentate amine phenol ligand. | 2003-03-10 |
|
| Synthesis of 11C-amides using [11C]carbon monoxide and in situ activated amines by palladium-mediated carboxaminations. | 2003-02-07 |
|
| Immobilizing a single pybox ligand onto a library of solid supports. | 2003 |
|
| [Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method]. | 2002-06 |
|
| Renal PGE2 production in the human and rat following phenacetin, acetaminophen and p-aminophenol. | 2002 |
|
| Effects of alternative carbon sources on biological transformation of nitrophenols. | 2002 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 19:21:56 GMT 2025
by
admin
on
Wed Apr 02 19:21:56 GMT 2025
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| Record UNII |
LW4E6Q6NWK
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| Record Status |
Validated (UNII)
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LW4E6Q6NWK
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23677025
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
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