NAN-190

COC1=CC=CC=C1N2CCN(CCCCN3C(=O)C4=C(C=CC=C4)C3=O)CC2

InChIKey=SJDOMIRMMUGQQK-UHFFFAOYSA-N

InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Serotonin 1a (5-HT1a) receptor 172 Target ID: CHEMBL273 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2976673	Antagonist 2778	0.58 nM [Ki]
Adrenergic receptor alpha-1 169 Target ID: CHEMBL1907610 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2976673	Binding Agent 1064	0.8 nM [Ki]
Serotonin 1b (5-HT1b) receptor 46 Target ID: CHEMBL3459 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2976673	Binding Agent 1064	62.0 nM [Ki]
Dopamine D2 receptor 297 Target ID: CHEMBL339 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2976673	Binding Agent 1064	60.0 nM [Ki]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:22:04 GMT 2023` Edited by `admin` on `Sat Dec 16 15:22:04 GMT 2023`
Record UNII	LQE19CTV54
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

NAN-190

Code

English

1H-ISOINDOLE-1,3(2H)-DIONE, 2-(4-(4-(2-METHOXYPHENYL)-1-PIPERAZINYL)BUTYL)-

Systematic Name

English

4-(2-METHOXYPHENYL)-1-(4-(N-PHTHALIMIDO)BUTYL)PIPERAZINE

Systematic Name

English

2-(4-(4-(2-METHOXYPHENYL)PIPERAZIN-1-YL)BUTYL)ISOINDOLE-1,3-DIONE

Systematic Name

English

2-(4-(4-(2-METHOXYPHENYL)-1-PIPERAZINYL)BUTYL)-1H-ISOINDOLE-1,3(2H)-DIONE

Systematic Name

English

1-(2-METHOXYPHENYL)-4-(4-PHTHALIMIDOBUTYL)PIPERAZINE

Systematic Name

English

Code System Code Type Description

CAS

102392-05-2