Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C25H25N5O |
| Molecular Weight | 411.4989 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CC2=C(C=C(C=C2)C3=C(C=CC(=N3)C#N)C4=CN(CC5(C)CCCC5)N=C4)C1=O
InChI
InChIKey=PREPVVXBTJBVOZ-UHFFFAOYSA-N
InChI=1S/C25H25N5O/c1-25(9-3-4-10-25)16-30-15-19(13-27-30)21-8-7-20(12-26)28-23(21)17-5-6-18-14-29(2)24(31)22(18)11-17/h5-8,11,13,15H,3-4,9-10,14,16H2,1-2H3
| Molecular Formula | C25H25N5O |
| Molecular Weight | 411.4989 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 01:07:05 GMT 2025
by
admin
on
Wed Apr 02 01:07:05 GMT 2025
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| Record UNII |
LP9S42UN97
|
| Record Status |
Validated (UNII)
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| Record Version |
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129285824
Created by
admin on Wed Apr 02 01:07:05 GMT 2025 , Edited by admin on Wed Apr 02 01:07:05 GMT 2025
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LP9S42UN97
Created by
admin on Wed Apr 02 01:07:05 GMT 2025 , Edited by admin on Wed Apr 02 01:07:05 GMT 2025
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300000044800
Created by
admin on Wed Apr 02 01:07:05 GMT 2025 , Edited by admin on Wed Apr 02 01:07:05 GMT 2025
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2102194-04-5
Created by
admin on Wed Apr 02 01:07:05 GMT 2025 , Edited by admin on Wed Apr 02 01:07:05 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET->POSITIVE ALLOSTERIC MODULATOR (PAM) |
Shown to be a PAM of ACh function in a cell-based Ca2+mobilization assay. In this assay, increasing concentrations of MK-6884 potentiated the ability of a fixed concentration of ACh (EC20) to mobilize intracellular Ca2+
ALLOSTERIC ACTIVATOR
EC50
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LABELED -> NON-LABELED |
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TARGET->POSITIVE ALLOSTERIC MODULATOR (PAM) |
BINDING
Ki
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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