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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 08:28:15 UTC 2023
Edited
by admin
on Sat Dec 16 08:28:15 UTC 2023
Protein Type TRANSPORTER
Protein Sub Type ORGANIC ANION
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
LGG1US7EOD
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OATL-4
Common Name English
OAT4L
Common Name English
URATE ANION EXCHANGER 1
Common Name English
URAT-1
Common Name English
SLC22A12
Common Name English
RST
Common Name English
OATL4
Common Name English
SOLUTE CARRIER FAMILY 22 MEMBER 12
Common Name English
URAT1
Common Name English
Classification Tree Code System Code
UCSF-FDA TRANSPORTAL SLC22A12
Created by admin on Sat Dec 16 08:28:15 UTC 2023 , Edited by admin on Sat Dec 16 08:28:15 UTC 2023
Code System Code Type Description
UNIPROT
Q96S37
Created by admin on Sat Dec 16 08:28:15 UTC 2023 , Edited by admin on Sat Dec 16 08:28:15 UTC 2023
PRIMARY
FDA UNII
LGG1US7EOD
Created by admin on Sat Dec 16 08:28:15 UTC 2023 , Edited by admin on Sat Dec 16 08:28:15 UTC 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_56
N 1_102
Related Record Type Details
Structure of LESINURAD
INHIBITOR -> TRANSPORTER
Structure of PROBENECID
INHIBITOR -> TRANSPORTER
Structure of Puliginurad
INHIBITOR -> TARGET
Structure of (2S,3S,4S,5R,6S)-6-(2-((3-(4-CYANO-1-NAPHTHYL)-4-PYRIDYL)SULFANYL)-2-METHYL-PROPANOYL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID
INHIBITOR -> TARGET
IC50
Structure of Arhalofenic Acid
INHIBITOR -> TARGET
Structure of LESINURAD
INHIBITOR -> TARGET
Structure of PRATOSARTAN
INHIBITOR -> TRANSPORTER
Structure of FENOFIBRIC ACID
INHIBITOR -> TRANSPORTER
Structure of SULFINPYRAZONE
INHIBITOR -> TRANSPORTER
Structure of LOSARTAN
INHIBITOR -> TRANSPORTER
Structure of 6-Hydroxybenzbromarone
INHIBITOR -> TARGET
IC50
Structure of DOTINURAD
INHIBITOR -> TARGET
IC50
Structure of VERINURAD
INHIBITOR -> TARGET
Structure of BENZBROMARONE
INHIBITOR -> TARGET
IC50
Structure of PROBENECID
INHIBITOR -> TARGET
Primary target.
Structure of URIC ACID
SUBSTRATE -> TRANSPORTER
In the human kidney, urate is transported (reabsorbed) via URAT1 across the apical membrane of proximal tubule cells, in exchange for anions being transported back into the tubule lumen to maintain electrical balance.
Structure of MORIN
INHIBITOR -> TRANSPORTER
Structure of RUZINURAD
INHIBITOR -> TARGET
Structure of TELMISARTAN
INHIBITOR -> TRANSPORTER
Structure of Xininurad
INHIBITOR -> TARGET
Structure of BENZBROMARONE
INHIBITOR -> TRANSPORTER
Structure of EPAMINURAD
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
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