MORIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H10O7
Molecular Weight	302.2357
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(C(O)=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2

InChI

InChIKey=YXOLAZRVSSWPPT-UHFFFAOYSA-N

InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H

HIDE SMILES / InChI

Molecular Formula	C15H10O7
Molecular Weight	302.2357
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
CHEMBL3833502 (Alpha glucosidase) 1 Target ID: CHEMBL3833502 (Alpha glucosidase) Sources: https://www.ncbi.nlm.nih.gov/pubmed/27549567	Inhibitor 8297	4.48 µM [IC50]
Protein-tyrosine phosphatase 1B 34 Target ID: CHEMBL335 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23352912	Inhibitor 8297
Islet amyloid polypeptide 1 Target ID: CHEMBL1914266 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22238175	Inhibitor 8297
DNA-3-methyladenine glycosylase 1 Target ID: CHEMBL3396943 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25650313	Inhibitor 8297	2.6 µM [IC50]

PubMed

Title	Date	PubMed
Steroid hormone activity of flavonoids and related compounds.	2000 Jul	10989984
Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines.	2000 Jul-Aug	10953322
Measurement of copper-binding sites on low density lipoprotein.	2001 Apr	11304478
Determinations of morin, quercetin and their conjugate metabolites in serum.	2001 Aug	11510497
Intestinal anti-inflammatory activity of morin on chronic experimental colitis in the rat.	2001 Dec	11736735
Aluminium toxicity in the rat brain: histochemical and immunocytochemical evidence.	2001 May 15	11470325
Interaction of morin with CTMAB: aggregation and location in micellar.	2001 Nov	11765782
Stability of green fluorescent protein using luminescence spectroscopy: is GFP applicable to field analysis of contaminants?	2002	12442776
Resonance double light scattering method for the determination of proteins with morin-CTMAB.	2002 Dec	12511091
Time resolved fluorescence spectroscopy of quercetin and morin complexes with Al3+.	2002 Jan 1	11808653
Chronic low-Ca/Mg high-Al diet induces neuronal loss.	2002 Sep	12416556
Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.	2003 Dec	14646185
Comparative study of flavonoids in experimental models of inflammation.	2003 Dec	14527825
Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock.	2003 Dec 26	14654167
Bioflavonoids attenuate renal proximal tubular cell injury during cold preservation in Euro-Collins and University of Wisconsin solutions.	2003 Feb	12631120
Flavonoid modulation of ionic currents mediated by GABA(A) and GABA(C) receptors.	2003 Feb 14	12586201
Morin applied in speciation of aluminium in natural waters and biological samples by reversed-phase high-performance liquid chromatography with fluorescence detection.	2003 Jun	12739101
Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy.	2003 Mar 12	12617605
Enantioselective synthesis of piperidine, indolizidine, and quinolizidine alkaloids from a phenylglycinol-derived delta-lactam.	2003 Mar 7	12608811
Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tert-butyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102.	2003 Sep 9	12972054
[Azoic color reaction of flavonoids and their analytical application].	2004 Aug	15766128
Free radicals scavenging efficiency of a few naturally occurring flavonoids: a comparative study.	2004 Dec 1	15563224
Variations and voids: the regulation of human cloning around the world.	2004 Dec 13	15596013
Inhibitory effects of flavonoids on animal fatty acid synthase.	2004 Jan	14999013
Absence of the TAP2 human recombination hotspot in chimpanzees.	2004 Jun	15208713
[Study on the fluorescence spectra of LaL3 with DNA].	2004 Mar	15759993
Inhibitory action of conventional food-grade natural antioxidants and of natural antioxidants of new development on the thermal-induced oxidation of cholesterol.	2004 Mar	14985188
[Communicative action for building nursing knowledge].	2004 Mar-Apr	15535528
Inhibitory effect of flavonoids on sulfo- and glucurono-conjugation of acetaminophen in rat cultured hepatocytes and liver subcellular preparations.	2004 May	15133252
[Speciation of aluminum in natural waters by fluorimetry].	2004 Nov	15762485
Flavone inhibition of tumor growth via apoptosis in vitro and in vivo.	2004 Sep	15289867
Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2.	2005 Feb 15	15670588
Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation.	2005 Mar	15649628

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:48:42 GMT 2023` Edited by `admin` on `Fri Dec 15 17:48:42 GMT 2023`
Record UNII	8NFQ3F76WR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MORIN

Common Name

English

2'-HYDROXYPELARGIDENOLON 1522

Common Name

English

C.I. NATURAL YELLOW 8

Common Name

English

C.I. 75660

Common Name

English

2-(2,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE

Systematic Name

English

OSAGE ORANGE EXTRACT

Common Name

English

NSC-19801

Code

English

MORIN [MI]

Common Name

English

2',3,4',5,7-PENTAHYDROXYFLAVONE

Systematic Name

English

Code System Code Type Description

NSC

19801