Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H10O7 |
| Molecular Weight | 302.2357 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=C(C(O)=C1)C2=C(O)C(=O)C3=C(O2)C=C(O)C=C3O
InChI
InChIKey=YXOLAZRVSSWPPT-UHFFFAOYSA-N
InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
| Molecular Formula | C15H10O7 |
| Molecular Weight | 302.2357 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL3833502 (Alpha glucosidase) Sources: https://www.ncbi.nlm.nih.gov/pubmed/27549567 |
4.48 µM [IC50] | ||
Target ID: CHEMBL335 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23352912 |
|||
Target ID: CHEMBL1914266 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22238175 |
|||
Target ID: CHEMBL3396943 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25650313 |
2.6 µM [IC50] |
PubMed
| Title | Date | PubMed |
|---|---|---|
| G-protein signaling: back to the future. | 2005-03 |
|
| Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation. | 2005-03 |
|
| Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. | 2005-02-15 |
|
| Investigation of dissolved uranium content in the watershed of Seine River (France). | 2005 |
|
| Variations and voids: the regulation of human cloning around the world. | 2004-12-13 |
|
| Free radicals scavenging efficiency of a few naturally occurring flavonoids: a comparative study. | 2004-12-01 |
|
| [Communicative action for building nursing knowledge]. | 2004-11-13 |
|
| [Speciation of aluminum in natural waters by fluorimetry]. | 2004-11 |
|
| Effects of morin on blood pressure and metabolic changes in fructose-induced hypertensive rats. | 2004-11 |
|
| [Granuloma with lymphocytic hyperplasia following vaccination: 10 cases. Presence of aluminium in the biopsies]. | 2004-10-27 |
|
| [Studies on a new fluorescence-enhanced system of nucleic acids-morin-Al(III)]. | 2004-10 |
|
| Flavone inhibition of tumor growth via apoptosis in vitro and in vivo. | 2004-09 |
|
| The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells. | 2004-08-15 |
|
| [Azoic color reaction of flavonoids and their analytical application]. | 2004-08 |
|
| Inhibitory effects of flavonoids on free radical-induced hemolysis and their oxidative effects on hemoglobin. | 2004-08 |
|
| Structural requirements of flavonoids for increment of ocular blood flow in the rabbit and retinal function recovery in rat eyes. | 2004-06 |
|
| Absence of the TAP2 human recombination hotspot in chimpanzees. | 2004-06 |
|
| Inhibition of free radical initiated peroxidation of human erythrocyte ghosts by flavonols and their glycosides. | 2004-05-07 |
|
| Inhibitory effect of flavonoids on sulfo- and glucurono-conjugation of acetaminophen in rat cultured hepatocytes and liver subcellular preparations. | 2004-05 |
|
| Inhibition of human low density lipoprotein oxidation by flavonols and their glycosides. | 2004-05 |
|
| Effects of alpha- and beta-cyclodextrin complexation on the physico-chemical properties and antioxidant activity of some 3-hydroxyflavones. | 2004-04-16 |
|
| Enhanced photoluminescence of morin-bovine serum albumin on porous anodized aluminum oxide. | 2004-04 |
|
| Differential effects of natural flavonoids on growth and iodide content in a human Na*/I- symporter-transfected follicular thyroid carcinoma cell line. | 2004-04 |
|
| Renin and angiotensinogen expression and functions in growth and apoptosis of human glioblastoma. | 2004-03-08 |
|
| Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease. | 2004-03-01 |
|
| [Study on the fluorescence spectra of LaL3 with DNA]. | 2004-03 |
|
| Structural aspects of flavonoids as trypsin inhibitors. | 2004-03 |
|
| Inhibitory action of conventional food-grade natural antioxidants and of natural antioxidants of new development on the thermal-induced oxidation of cholesterol. | 2004-03 |
|
| Faculty matters. Karen H. Morin. | 2004-02-07 |
|
| Double urine circulation: importance of pores. | 2004-01-23 |
|
| Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake. | 2004-01-09 |
|
| Evaluation of ultrasonographic angle and linear parameters in the diagnosis of developmental dysplasia of the hip. | 2004-01 |
|
| Inhibitory effects of flavonoids on animal fatty acid synthase. | 2004-01 |
|
| Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. | 2003-12-26 |
|
| Reaction rate constants of superoxide scavenging by plant antioxidants. | 2003-12-15 |
|
| PubMatrix: a tool for multiplex literature mining. | 2003-12-10 |
|
| Flavones inhibit proliferation and increase mediator content in human leukemic mast cells (HMC-1). | 2003-12 |
|
| Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. | 2003-12 |
|
| Comparative study of flavonoids in experimental models of inflammation. | 2003-12 |
|
| Inhibitory effects of plant-derived flavonoids and phenolic acids on malonaldehyde formation from ethyl arachidonate. | 2003-11-19 |
|
| Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta. | 2003-10-06 |
|
| Different antioxidant effects of polyphenols on lipid peroxidation and hydroxyl radicals in the NADPH-, Fe-ascorbate- and Fe-microsomal systems. | 2003-10-01 |
|
| Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease. | 2003-10 |
|
| Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tert-butyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102. | 2003-09-09 |
|
| Paclitaxel metabolism in rat and human liver microsomes is inhibited by phenolic antioxidants. | 2003-09 |
|
| Effects of flavonoids on the susceptibility of low-density lipoprotein to oxidative modification. | 2003-07 |
|
| Pro-oxidative properties of flavonoids in human lymphocytes. | 2003-06 |
|
| Anti-oxidant effect of flavonoids on the susceptibility of LDL oxidation. | 2003-04 |
|
| The inhibitory effects of pure flavonoids on in vitro protein glycosylation. | 2002 |
|
| Flavones are inhibitors of HIV-1 proteinase. | 1992-10-30 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:53:26 GMT 2025
by
admin
on
Mon Mar 31 18:53:26 GMT 2025
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| Record UNII |
8NFQ3F76WR
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| Record Status |
Validated (UNII)
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| Record Version |
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19801
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8NFQ3F76WR
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5281670
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207-542-9
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m7625
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C008548
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480-16-0
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75092
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DTXSID1022398
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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