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Details

Stereochemistry ACHIRAL
Molecular Formula C15H10O7
Molecular Weight 302.2357
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MORIN

SMILES

OC1=CC=C(C(O)=C1)C2=C(O)C(=O)C3=C(O2)C=C(O)C=C3O

InChI

InChIKey=YXOLAZRVSSWPPT-UHFFFAOYSA-N
InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H

HIDE SMILES / InChI

Molecular Formula C15H10O7
Molecular Weight 302.2357
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: CHEMBL3833502 (Alpha glucosidase)
4.48 µM [IC50]
2.6 µM [IC50]
PubMed

PubMed

TitleDatePubMed
G-protein signaling: back to the future.
2005-03
Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation.
2005-03
Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2.
2005-02-15
Investigation of dissolved uranium content in the watershed of Seine River (France).
2005
Variations and voids: the regulation of human cloning around the world.
2004-12-13
Free radicals scavenging efficiency of a few naturally occurring flavonoids: a comparative study.
2004-12-01
[Communicative action for building nursing knowledge].
2004-11-13
[Speciation of aluminum in natural waters by fluorimetry].
2004-11
Effects of morin on blood pressure and metabolic changes in fructose-induced hypertensive rats.
2004-11
[Granuloma with lymphocytic hyperplasia following vaccination: 10 cases. Presence of aluminium in the biopsies].
2004-10-27
[Studies on a new fluorescence-enhanced system of nucleic acids-morin-Al(III)].
2004-10
Flavone inhibition of tumor growth via apoptosis in vitro and in vivo.
2004-09
The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells.
2004-08-15
[Azoic color reaction of flavonoids and their analytical application].
2004-08
Inhibitory effects of flavonoids on free radical-induced hemolysis and their oxidative effects on hemoglobin.
2004-08
Structural requirements of flavonoids for increment of ocular blood flow in the rabbit and retinal function recovery in rat eyes.
2004-06
Absence of the TAP2 human recombination hotspot in chimpanzees.
2004-06
Inhibition of free radical initiated peroxidation of human erythrocyte ghosts by flavonols and their glycosides.
2004-05-07
Inhibitory effect of flavonoids on sulfo- and glucurono-conjugation of acetaminophen in rat cultured hepatocytes and liver subcellular preparations.
2004-05
Inhibition of human low density lipoprotein oxidation by flavonols and their glycosides.
2004-05
Effects of alpha- and beta-cyclodextrin complexation on the physico-chemical properties and antioxidant activity of some 3-hydroxyflavones.
2004-04-16
Enhanced photoluminescence of morin-bovine serum albumin on porous anodized aluminum oxide.
2004-04
Differential effects of natural flavonoids on growth and iodide content in a human Na*/I- symporter-transfected follicular thyroid carcinoma cell line.
2004-04
Renin and angiotensinogen expression and functions in growth and apoptosis of human glioblastoma.
2004-03-08
Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease.
2004-03-01
[Study on the fluorescence spectra of LaL3 with DNA].
2004-03
Structural aspects of flavonoids as trypsin inhibitors.
2004-03
Inhibitory action of conventional food-grade natural antioxidants and of natural antioxidants of new development on the thermal-induced oxidation of cholesterol.
2004-03
Faculty matters. Karen H. Morin.
2004-02-07
Double urine circulation: importance of pores.
2004-01-23
Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.
2004-01-09
Evaluation of ultrasonographic angle and linear parameters in the diagnosis of developmental dysplasia of the hip.
2004-01
Inhibitory effects of flavonoids on animal fatty acid synthase.
2004-01
Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock.
2003-12-26
Reaction rate constants of superoxide scavenging by plant antioxidants.
2003-12-15
PubMatrix: a tool for multiplex literature mining.
2003-12-10
Flavones inhibit proliferation and increase mediator content in human leukemic mast cells (HMC-1).
2003-12
Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
2003-12
Comparative study of flavonoids in experimental models of inflammation.
2003-12
Inhibitory effects of plant-derived flavonoids and phenolic acids on malonaldehyde formation from ethyl arachidonate.
2003-11-19
Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta.
2003-10-06
Different antioxidant effects of polyphenols on lipid peroxidation and hydroxyl radicals in the NADPH-, Fe-ascorbate- and Fe-microsomal systems.
2003-10-01
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease.
2003-10
Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tert-butyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102.
2003-09-09
Paclitaxel metabolism in rat and human liver microsomes is inhibited by phenolic antioxidants.
2003-09
Effects of flavonoids on the susceptibility of low-density lipoprotein to oxidative modification.
2003-07
Pro-oxidative properties of flavonoids in human lymphocytes.
2003-06
Anti-oxidant effect of flavonoids on the susceptibility of LDL oxidation.
2003-04
The inhibitory effects of pure flavonoids on in vitro protein glycosylation.
2002
Flavones are inhibitors of HIV-1 proteinase.
1992-10-30
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:53:26 GMT 2025
Edited
by admin
on Mon Mar 31 18:53:26 GMT 2025
Record UNII
8NFQ3F76WR
Record Status Validated (UNII)
Record Version
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Name Type Language
NSC-19801
Preferred Name English
MORIN
MI  
Common Name English
2'-HYDROXYPELARGIDENOLON 1522
Common Name English
C.I. NATURAL YELLOW 8
Common Name English
C.I. 75660
Common Name English
2-(2,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE
Systematic Name English
OSAGE ORANGE EXTRACT
Common Name English
MORIN [MI]
Common Name English
2',3,4',5,7-PENTAHYDROXYFLAVONE
Systematic Name English
Code System Code Type Description
NSC
19801
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
FDA UNII
8NFQ3F76WR
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
PUBCHEM
5281670
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
ECHA (EC/EINECS)
207-542-9
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
MERCK INDEX
m7625
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY Merck Index
MESH
C008548
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
CAS
480-16-0
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
CHEBI
75092
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
EPA CompTox
DTXSID1022398
Created by admin on Mon Mar 31 18:53:26 GMT 2025 , Edited by admin on Mon Mar 31 18:53:26 GMT 2025
PRIMARY
Related Record Type Details
TRANSPORTER -> INHIBITOR