U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:46:22 GMT 2023
Edited
by admin
on Sat Dec 16 13:46:22 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
L9E2OD8XIY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALPHA-SYNUCLEIN
Common Name English
SYNUCLEIN ALPHA
Common Name English
NACP
Common Name English
PARK1
Common Name English
NON-A BETA COMPONENT OF AD AMYLOID
Common Name English
NON-A4 COMPONENT OF AMYLOID PRECURSOR
Common Name English
Code System Code Type Description
FDA UNII
L9E2OD8XIY
Created by admin on Sat Dec 16 13:46:22 GMT 2023 , Edited by admin on Sat Dec 16 13:46:22 GMT 2023
PRIMARY
UNIPROT
P37840
Created by admin on Sat Dec 16 13:46:22 GMT 2023 , Edited by admin on Sat Dec 16 13:46:22 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR OF AGGREGATION->TARGET
INHIBITOR OF AGGREGATION->TARGET
INHIBITOR OF EXPRESSION->TARGET
INHIBITOR -> TARGET
INHIBITOR OF AGGREGATION->TARGET
INHIBITOR OF AGGREGATION->TARGET
Reduced the accumulation of a-syn in vivo, and upregulated LC3 expression, both in vitro and in vivo, suggests that NPT520-34 may influence protein clearance mechanisms for pathological proteins.
INHIBITOR -> TARGET
INHIBITOR OF AGGREGATION->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL