Lofacimig

Investigational

Approval Year

Substance Class	Protein
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	L55HB62LXD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Lofacimig

Official Name

English

H-gamma1 heavy chain VH-VH-G1(h-CH2-CH3) (1-493) [VH anti-F11 apple 2 domain (Camelus dromedarius IGHV3S45*01 (86.6%)/Homo sapiens IGHV3-66*01 (83.5%) -(IGHD) -IGHJ5*02 (100%), CDR-IMGT [9.7.23] (26-34.52-58.97-119)) (1-130) -3-mer (glycyl-alanyl-prolyl)

Preferred Name

English

only-heavy-chain immunoglobulin VH-VH-G1(h-CH2-CH3) dimer, anti-[Homo sapiens F11 (coagulation factor XI, FXI, plasma thromboplastin antecedent, PTA) apple 2 domain] and anti-[Homo sapiens F11 (coagulation factor XI, FXI, plasma thromboplastin antecedent

Common Name

English

Immunoglobulin, biparatropic, anti-(human coagulation factor XI Apple 2 domain) (human-Lama glama monoclonal KN060 single-domain VHH fragment) fusion protein with peptide linker (GAP) fusion protein with immunoglobulin anti-(human coagulation factor XI A

Common Name

English

lofacimig [INN]

Common Name

English

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