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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H19F2N5O4
Molecular Weight 407.3714
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GDC-0077

SMILES

C[C@H](NC1=CC=C2C3=NC(=CN3CCOC2=C1)N4[C@@H](COC4=O)C(F)F)C(N)=O

InChI

InChIKey=SGEUNORSOZVTOL-CABZTGNLSA-N
InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11)24)25-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26)/t9-,12-/m0/s1

HIDE SMILES / InChI

Molecular Formula C18H19F2N5O4
Molecular Weight 407.3714
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.038 nM [IC50]
Substance Class Chemical
Created
by admin
on Tue Oct 22 08:44:30 UTC 2019
Edited
by admin
on Tue Oct 22 08:44:30 UTC 2019
Record UNII
L4C1UY2NYH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GDC-0077
Code English
PROPANAMIDE, 2-((2-((4S)-4-(DIFLUOROMETHYL)-2-OXO-3-OXAZOLIDINYL)-5,6-DIHYDROIMIDAZO(1,2-D)(1,4)BENZOXAZEPIN-9-YL)AMINO)-, (2S)-
Systematic Name English
GDC0077
Code English
Code System Code Type Description
CAS
2060571-02-8
Created by admin on Tue Oct 22 08:44:30 UTC 2019 , Edited by admin on Tue Oct 22 08:44:30 UTC 2019
PRIMARY
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TARGET -> INHIBITOR
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METABOLIC ENZYME -> SUBSTRATE
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ACTIVE MOIETY