Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H19F2N5O4 |
| Molecular Weight | 407.3714 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H](NC1=CC=C2C3=NC(=CN3CCOC2=C1)N4[C@@H](COC4=O)C(F)F)C(N)=O
InChI
InChIKey=SGEUNORSOZVTOL-CABZTGNLSA-N
InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11)24)25-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26)/t9-,12-/m0/s1
| Molecular Formula | C18H19F2N5O4 |
| Molecular Weight | 407.3714 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Oct 22 08:44:30 UTC 2019
by
admin
on
Tue Oct 22 08:44:30 UTC 2019
|
| Record UNII |
L4C1UY2NYH
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Code | English | ||
|
Systematic Name | English | ||
|
Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
2060571-02-8
Created by
admin on Tue Oct 22 08:44:30 UTC 2019 , Edited by admin on Tue Oct 22 08:44:30 UTC 2019
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
TARGET -> INHIBITOR |
selective for alpha isoform, and leads to degradation of mutant p110 alpha PI3K subunit.
|
||
|
|
METABOLIC ENZYME -> SUBSTRATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
