Oloctinebart

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:00:20 GMT 2025` Edited by `admin` on `Wed Apr 02 10:00:20 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	KN8YN5E9D5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Oloctinebart

Official Name

English

Immunoglobulin G4 [224-proline,de-C-terminal-lysine], anti-(human galectin-3) (human-Mus musculus monoclonal TB006 ?4-chain), disulfide with human-Mus musculus monoclonal TB006 ?-chain, dimer

Preferred Name

English

Immunoglobulin G4-kappa, anti-[Homo sapiens LGALS3 (galectin 3)], humanized monoclonal antibody (gamma4 heavy chain humanized (1-442) [VH (Homo sapiens IGHV1-3*01 (88.7%) -(IGHD) -IGHJ6*01 (93.3%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116)-Homo sapi

Common Name

English

oloctinebart [INN]

Common Name

English

Code System Code Type Description

INN

12421

Created by admin on Wed Apr 02 10:00:20 GMT 2025 , Edited by admin on Wed Apr 02 10:00:20 GMT 2025

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FDA UNII

KN8YN5E9D5

Created by admin on Wed Apr 02 10:00:20 GMT 2025 , Edited by admin on Wed Apr 02 10:00:20 GMT 2025

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CAS

2669063-84-5

Created by admin on Wed Apr 02 10:00:20 GMT 2025 , Edited by admin on Wed Apr 02 10:00:20 GMT 2025

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NCI_THESAURUS

C199082

Created by admin on Wed Apr 02 10:00:20 GMT 2025 , Edited by admin on Wed Apr 02 10:00:20 GMT 2025

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SMS_ID

300000050077

Created by admin on Wed Apr 02 10:00:20 GMT 2025 , Edited by admin on Wed Apr 02 10:00:20 GMT 2025

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From	To
4_139	4_199
4_23	4_93
3_139	3_199
3_23	3_93
2_363	2_421
2_257	2_317
2_143	2_199
2_130	4_219
2_22	2_96
1_363	1_421
1_257	1_317
1_225	2_225
1_222	2_222
1_130	3_219
1_143	1_199
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_293
N	2_293

Related Record Type Details


					KN8YN5E9D5

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL