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Details

Stereochemistry ACHIRAL
Molecular Formula C10H8N4O5
Molecular Weight 264.1943
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of FURAZIDINE

SMILES

[O-][N+](=O)C1=CC=C(O1)\C=C\C=N\N2CC(=O)NC2=O

InChI

InChIKey=DECBQELQORZLLP-UAIOPKHMSA-N
InChI=1S/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+

HIDE SMILES / InChI

Molecular Formula C10H8N4O5
Molecular Weight 264.1943
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 2
Optical Activity NONE

Description

Furagin (Furazidine) is a nitrofuran derivative, acting as an antibacterial medicine with bacteriostatic action. It is active against both gram-positive (Staphylococcus epidermidis, Staphylococcus aureus, Staphylococcus faecalis) and gram-negative microorganisms (Enterobacteriaceae – Salmonella, Shygella, Proteus, Klebsiella, Escherichia, Enterobacter, etc.). It is used for the treatment of urinary tract, skin and soft tissues infections.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Furagin
Curative
Furagin

PubMed

Sample Use Guides

In Vivo Use Guide
Adults: 50-100 mg t.i.d., for 7-14 days. 0.5% or 1% solution for topical applications.
Route of Administration: Other
In Vitro Use Guide
Furagin (Furazidine) is a broad-spectrum antimicrobial agent belonging to the group of nitrofurans. Against the majority of bacteria, the bacteriostatic concentration ranges from 1: 100,000 to 1: 200,000; bactericidal - about 2 times more.
Substance Class Chemical
Record UNII
K2R4N34Y9I
Record Status Validated (UNII)
Record Version