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Details

Stereochemistry ACHIRAL
Molecular Formula C10H7N4O5.Na
Molecular Weight 286.1761
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of FURAZIDINE SODIUM

SMILES

[Na+].[O-][N+](=O)C1=CC=C(O1)\C=C\C=N\N2CC(=O)[N-]C2=O

InChI

InChIKey=LNKQENVGMUHHIX-NGTWICJZSA-M
InChI=1S/C10H8N4O5.Na/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18;/h1-5H,6H2,(H,12,15,16);/q;+1/p-1/b2-1+,11-5+;

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C10H8N4O5
Molecular Weight 264.1943
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 2
Optical Activity NONE

Furagin (Furazidine) is a nitrofuran derivative, acting as an antibacterial medicine with bacteriostatic action. It is active against both gram-positive (Staphylococcus epidermidis, Staphylococcus aureus, Staphylococcus faecalis) and gram-negative microorganisms (Enterobacteriaceae – Salmonella, Shygella, Proteus, Klebsiella, Escherichia, Enterobacter, etc.). It is used for the treatment of urinary tract, skin and soft tissues infections.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Furagin

Approved Use

Furagin (Furazidine) is indicated for the treatment of urinary tract infections. Topical furagin is used in the treatment of infections of the skin and soft tissues.
Curative
Furagin

Approved Use

Furagin (Furazidine) is indicated for the treatment of urinary tract infections. Topical furagin is used in the treatment of infections of the skin and soft tissues.
PubMed

PubMed

TitleDatePubMed
[Experimental studies on a new chemotherapeutic preparation furazidin].
1958 Jul
Pharmacokinetics of furagin, a new nitrofurantoin congener, on human volunteers.
1979 Jun
Ciprofloxacin and furagin in acute cystitis: comparison of early immune and microbiological results.
2008 Feb
Patents

Sample Use Guides

Adults: 50-100 mg t.i.d., for 7-14 days. 0.5% or 1% solution for topical applications.
Route of Administration: Other
Furagin (Furazidine) is a broad-spectrum antimicrobial agent belonging to the group of nitrofurans. Against the majority of bacteria, the bacteriostatic concentration ranges from 1: 100,000 to 1: 200,000; bactericidal - about 2 times more.
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:26:45 GMT 2023
Edited
by admin
on Sat Dec 16 10:26:45 GMT 2023
Record UNII
PD0LSG5BP0
Record Status Validated (UNII)
Record Version
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Name Type Language
FURAZIDINE SODIUM
Common Name English
FURAZIDIN SODIUM
Common Name English
HYDANTOIN, 1-((3-(5-NITRO-2-FURYL)ALLYLIDENE)AMINO)-, MONOSODIUM SALT
Systematic Name English
AKRITOIN SODIUM
Common Name English
Furazidin sodium [WHO-DD]
Common Name English
2,4-IMIDAZOLIDINEDIONE, 1-((3-(5-NITRO-2-FURANYL)-2-PROPEN-1-YLIDENE)AMINO)-, SODIUM SALT (1:1)
Systematic Name English
Code System Code Type Description
SMS_ID
100000177766
Created by admin on Sat Dec 16 10:26:46 GMT 2023 , Edited by admin on Sat Dec 16 10:26:46 GMT 2023
PRIMARY
PUBCHEM
119025833
Created by admin on Sat Dec 16 10:26:46 GMT 2023 , Edited by admin on Sat Dec 16 10:26:46 GMT 2023
PRIMARY
FDA UNII
PD0LSG5BP0
Created by admin on Sat Dec 16 10:26:46 GMT 2023 , Edited by admin on Sat Dec 16 10:26:46 GMT 2023
PRIMARY
CAS
22060-47-5
Created by admin on Sat Dec 16 10:26:46 GMT 2023 , Edited by admin on Sat Dec 16 10:26:46 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY