UREFIBRATE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H12Cl2N2O4
Molecular Weight	355.173
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of UREFIBRATE

Structure Search

SMILES

NC(=O)NC(=O)C(OC1=CC=C(Cl)C=C1)OC2=CC=C(Cl)C=C2

InChI

InChIKey=SARMXBVJUDMWKA-UHFFFAOYSA-N

InChI=1S/C15H12Cl2N2O4/c16-9-1-5-11(6-2-9)22-14(13(20)19-15(18)21)23-12-7-3-10(17)4-8-12/h1-8,14H,(H3,18,19,20,21)

HIDE SMILES / InChI

Molecular Formula	C15H12Cl2N2O4
Molecular Weight	355.173
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://apps.who.int/iris/bitstream/handle/10665/275695/WHO-EMP-RHT-TSN-2018.1-eng.pdf?sequence=1&isAllowed=y | https://www.who.int/medicines/services/inn/RevisedFinalStemBook2006.pdf

Urefibrate, clofibrate derivative, is a peroxisome proliferator activated receptor-α (PPAR-α) agonist. It is an antihyperlipidaemic agent.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[The effect of clofibrate (ethyl-p-chlorophenoxy isobutyrate), M-451 (bis-p-chlorophenoxy-acetylurea) and phenobarbital on experimental liver damage in rats].	1974 Mar	4849902

Patents

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:42:32 GMT 2023` Edited by `admin` on `Sat Dec 16 16:42:32 GMT 2023`
Record UNII	K0T77AAY7G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

UREFIBRATE

Official Name

English

urefibrate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C98150

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

Code System Code Type Description

INN

4239

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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SMS_ID

100000076645

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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FDA UNII

K0T77AAY7G

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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EVMPD

SUB11387MIG

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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ChEMBL

CHEMBL2107699

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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EPA CompTox

DTXSID70191959

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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NCI_THESAURUS

C75262

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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MESH

C025095

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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PUBCHEM

65809

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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CAS

38647-79-9

Created by admin on Sat Dec 16 16:42:32 GMT 2023 , Edited by admin on Sat Dec 16 16:42:32 GMT 2023

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					K0T77AAY7G

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