DIHEXYVERINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H35NO2
Molecular Weight	321.4974
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C(OCCN1CCCCC1)C2(CCCCC2)C3CCCCC3

InChI

InChIKey=MNSQDVCVWNXBFQ-UHFFFAOYSA-N

InChI=1S/C20H35NO2/c22-19(23-17-16-21-14-8-3-9-15-21)20(12-6-2-7-13-20)18-10-4-1-5-11-18/h18H,1-17H2

HIDE SMILES / InChI

Molecular Formula	C20H35NO2
Molecular Weight	321.4974
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugfuture.com/chemdata/dihexyverine.html | https://www.ncbi.nlm.nih.gov/pubmed/13944939 | https://www.ncbi.nlm.nih.gov/pubmed/13294387 | http://sante.lefigaro.fr/medicaments/3098815-spasmodex-10mg-2ml-amp-im-6 | https://www.onmeda.fr/medicament/spasmodex-93098838.html

Dihexyverine (Metaspas, Spasmodex) is an anticholinergic and direct smooth muscle relaxant (spasmolytic). Dihexyverine is sold in France under the brand name Spasmodex. It is indicated for the treatment of the gastrointestinal tract disorders. Dihexyverine is a muscarinic acetylcholine receptor antagonist.

Approval Year

PubMed

Title	Date	PubMed
[Preliminary clinical study on the use of dihexyverine in obstetrics].	1962-11-24	13944939
[Trial therapy of spastic cough with a new synthetic antispasmodic: dihexyverine].	1955-12-25	13294387

Patents

Sample Use Guides

In Vivo Use Guide

One hundred and five patients constituted the series: 31 were primiparae, 27 secundiparae and 47 multiparae. The majority of these (95) received one intramuscular injection (10 mg) of dihexyverine.

Route of Administration: Intramuscular

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:08:10 GMT 2025` Edited by `admin` on `Mon Mar 31 19:08:10 GMT 2025`
Record UNII	J2FQ66RU9W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

(1,1'-BICYCLOHEXYL)-1-CARBOXYLIC ACID, 2-(1-PIPERIDINYL)ETHYL ESTER

Preferred Name

English

DIHEXYVERINE

Official Name

English

Dihexyverine [WHO-DD]

Common Name

English

dihexyverine [INN]

Common Name

English

DIHEXYVERINE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29704