DIHEXYVERINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H35NO2
Molecular Weight	321.4974
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DIHEXYVERINE

Structure Search

SMILES

O=C(OCCN1CCCCC1)C2(CCCCC2)C3CCCCC3

InChI

InChIKey=MNSQDVCVWNXBFQ-UHFFFAOYSA-N

InChI=1S/C20H35NO2/c22-19(23-17-16-21-14-8-3-9-15-21)20(12-6-2-7-13-20)18-10-4-1-5-11-18/h18H,1-17H2

HIDE SMILES / InChI

Molecular Formula	C20H35NO2
Molecular Weight	321.4974
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugfuture.com/chemdata/dihexyverine.html | https://www.ncbi.nlm.nih.gov/pubmed/13944939 | https://www.ncbi.nlm.nih.gov/pubmed/13294387 | http://sante.lefigaro.fr/medicaments/3098815-spasmodex-10mg-2ml-amp-im-6 | https://www.onmeda.fr/medicament/spasmodex-93098838.html

Dihexyverine (Metaspas, Spasmodex) is an anticholinergic and direct smooth muscle relaxant (spasmolytic). Dihexyverine is sold in France under the brand name Spasmodex. It is indicated for the treatment of the gastrointestinal tract disorders. Dihexyverine is a muscarinic acetylcholine receptor antagonist.

Approval Year

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Sample Use Guides

In Vivo Use Guide

One hundred and five patients constituted the series: 31 were primiparae, 27 secundiparae and 47 multiparae. The majority of these (95) received one intramuscular injection (10 mg) of dihexyverine.

Route of Administration: Intramuscular

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:12:21 GMT 2023` Edited by `admin` on `Fri Dec 15 18:12:21 GMT 2023`
Record UNII	J2FQ66RU9W
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIHEXYVERINE

Official Name

English

Dihexyverine [WHO-DD]

Common Name

English

dihexyverine [INN]

Common Name

English

(1,1'-BICYCLOHEXYL)-1-CARBOXYLIC ACID, 2-(1-PIPERIDINYL)ETHYL ESTER

Common Name

English

DIHEXYVERINE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29704

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

NCI_THESAURUS

C29698

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

WHO-VATC

QA03AA08

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

WHO-ATC

A03AA08

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

Code System Code Type Description

MERCK INDEX

m1114

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

PRIMARY

Merck Index

EVMPD

SUB07136MIG

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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RXCUI

236209

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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RxNorm

CAS

561-77-3

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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NCI_THESAURUS

C97978

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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ChEMBL

CHEMBL2110912

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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EPA CompTox

DTXSID80204645

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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WIKIPEDIA

DIHEXYVERINE

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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INN

361

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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DRUG CENTRAL

883

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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SMS_ID

100000082605

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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DRUG BANK

DB13678

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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FDA UNII

J2FQ66RU9W

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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PUBCHEM

21788

Created by admin on Fri Dec 15 18:12:21 GMT 2023 , Edited by admin on Fri Dec 15 18:12:21 GMT 2023

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Related Record Type Details


					336704VYVB

DIHEXYVERINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					J2FQ66RU9W

ACTIVE MOIETY