DIHEXYVERINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H35NO2.ClH
Molecular Weight	357.958
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.O=C(OCCN1CCCCC1)C2(CCCCC2)C3CCCCC3

InChI

InChIKey=AQFATCCHOXBYNK-UHFFFAOYSA-N

InChI=1S/C20H35NO2.ClH/c22-19(23-17-16-21-14-8-3-9-15-21)20(12-6-2-7-13-20)18-10-4-1-5-11-18;/h18H,1-17H2;1H

HIDE SMILES / InChI

Molecular Formula	C20H35NO2
Molecular Weight	321.4974
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugfuture.com/chemdata/dihexyverine.html | https://www.ncbi.nlm.nih.gov/pubmed/13944939 | https://www.ncbi.nlm.nih.gov/pubmed/13294387 | http://sante.lefigaro.fr/medicaments/3098815-spasmodex-10mg-2ml-amp-im-6 | https://www.onmeda.fr/medicament/spasmodex-93098838.html

Dihexyverine (Metaspas, Spasmodex) is an anticholinergic and direct smooth muscle relaxant (spasmolytic). Dihexyverine is sold in France under the brand name Spasmodex. It is indicated for the treatment of the gastrointestinal tract disorders. Dihexyverine is a muscarinic acetylcholine receptor antagonist.

Approval Year

PubMed

Title	Date	PubMed
[Trial therapy of spastic cough with a new synthetic antispasmodic: dihexyverine].	1955 Dec 25	13294387
[Preliminary clinical study on the use of dihexyverine in obstetrics].	1962 Nov 24	13944939

Patents

Sample Use Guides

In Vivo Use Guide

One hundred and five patients constituted the series: 31 were primiparae, 27 secundiparae and 47 multiparae. The majority of these (95) received one intramuscular injection (10 mg) of dihexyverine.

Route of Administration: Intramuscular

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:36:13 UTC 2023` Edited by `admin` on `Fri Dec 15 15:36:13 UTC 2023`
Record UNII	336704VYVB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIHEXYVERINE HYDROCHLORIDE

Official Name

English

2-Piperidinoethyl ester of bicyclohexyl-1-carboxylic acid hydrochloride

Common Name

English

DIHEXYVERINE HYDROCHLORIDE [MART.]

Common Name

English

DIHEXYVERINE HYDROCHLORIDE [MI]

Common Name

English

(1,1'-BICYCLOHEXYL)-1-CARBOXYLIC ACID, 2-(1-PIPERIDINYL)ETHYL ESTER HYDROCHLORIDE

Common Name

English

JL-1078

Code

English

DIHEXYVERINE HYDROCHLORIDE [USAN]

Common Name

English

Dihexyverine hydrochloride [WHO-DD]

Common Name

English

DIHEXYVERINE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29704