U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2C5H9O2.Zn
Molecular Weight 267.657
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZINC VALERATE

SMILES

[Zn++].CCCCC([O-])=O.CCCCC([O-])=O

InChI

InChIKey=BUDAIZWUWHWZPQ-UHFFFAOYSA-L
InChI=1S/2C5H10O2.Zn/c2*1-2-3-4-5(6)7;/h2*2-4H2,1H3,(H,6,7);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula Zn
Molecular Weight 65.409
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H9O2
Molecular Weight 101.1238
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Valeric acid is a colorless, oily liquid with an unpleasant odor. It is highly corrosive and must be handled with care. Valeric acid is mainly used as a chemical intermediate to manufacture flavors and perfumes, synthetic lubricants, agricultural chemicals, and pharmaceuticals. It is also used as a flavoring aid in foods. Valeric acid is considered safe as a food additive by the World Health Organization.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids.
2004-03
Sequential feeding of glucose and valerate in a fed-batch culture of Ralstonia eutropha for production of poly(hydroxybutyrate-co-hydroxyvalerate) with high 3-hydroxyvalerate fraction.
2004-02-07
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.
2004-01-27
The degradability of biodegradable plastics in aerobic and anaerobic waste landfill model reactors.
2004-01
Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation.
2003-11-21
Ruminal fermentation and bacterial protein synthesis of whole cottonseed coated with combinations of gelatinized corn starch and urea.
2003-11
Pelleted beet pulp substituted for high-moisture corn: 3. Effects on ruminal fermentation, pH, and microbial protein efficiency in lactating dairy cows.
2003-11
Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate.
2003-10-20
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha.
2003-10-17
Synthesis, X-ray crystal structure, UV/visible linear and nonlinear (optical limiting) spectral properties of symmetrical and unsymmetrical porphyrazines with annulated 1,2,5-thiadiazole and 1,4-diamyloxybenzene moieties.
2003-09-05
Conformationally constrained analogues of bleomycin A5.
2003-08-27
[Anti-arrhythmia activity of estradiol valerate and estradiol nitrate].
2003-08-20
Synthesis and cytotoxicity of new platinum(IV) complexes of mixed carboxylates.
2003-08-01
Eubacterium pyruvativorans sp. nov., a novel non-saccharolytic anaerobe from the rumen that ferments pyruvate and amino acids, forms caproate and utilizes acetate and propionate.
2003-07
Efficacy of betamethasone valerate foam formulation in comparison with betamethasone dipropionate lotion in the treatment of mild-to-moderate alopecia areata: a multicenter, prospective, randomized, controlled, investigator-blinded trial.
2003-07
Dynamics of the anaerobic process: effects of volatile fatty acids.
2003-06-30
Parameter identification of thermophilic anaerobic degradation of valerate.
2003-06-10
Heterogeneous acylation of flax fibers. Reaction kinetics and surface properties.
2003-05-14
Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69.
2003-05
Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids.
2003-04-18
Activation of neurons in trigeminal caudalis by noxious oral acidic or salt stimuli is not reduced by amiloride.
2003-04-18
Psychophysical evaluation of responses to pleasant and mal-odour stimulation in human subjects; adaptation, dose response and gender differences.
2003-04
Effects of hydrochloric, valeric, and other volatile fatty acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses.
2003-04
Effects of hormone replacement therapy on perceptual and cognitive event-related potentials in menopausal insomnia.
2003-04
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
2003-03-28
Left ventricular diastolic function assessment by tissue Doppler echocardiography in relation to hormonal replacement therapy in postmenopausal women with diastolic dysfunction.
2003-03-12
Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution.
2003-03
Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis.
2003-03
Optimizing the level of wet corn gluten feed in the diet of lactating dairy cows.
2003-03
Polymers for biodegradable medical devices XI. Microencapsulation studies: characterization of hydrocortisone-loaded poly-hydroxybutyrate-hydroxyvalerate microspheres.
2003-02-06
Effect of method of application of a fibrolytic enzyme product on digestive processes and milk production in Holstein-Friesian cows.
2003-02
Enhanced biosynthesis of polyhydroxyalkanoates in a mutant strain of Rhizobium meliloti.
2003-01
Production of purified polyhydroxyalkanoates (PHAs) for applications in contact with blood.
2003
Liquefaction and methanization of solid and liquid coffee wastes by two phase anaerobic digestion process.
2003
Hydrogen production from wastewater by acidogenic granular sludge.
2003
Oestrogen therapy for prevention of reinfarction in postmenopausal women: a randomised placebo controlled trial.
2002-12-31
Hormone replacement therapy and vigilance: double-blind, placebo-controlled EEG-mapping studies with an estrogen-progestogen combination (Climodien, Lafamme) versus estrogen alone in menopausal syndrome patients.
2002-11-20
Acylated triterpenoid saponins from the stem bark of Foetidia africana.
2002-11
Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells.
2002-10-04
Characterization of copolymer hydroxybutyrate/hydroxyvalerate from saponified vernonia, soybean, and "spent" frying oils.
2002-08-16
A novel synthesis of (+)-biotin from L-cysteine.
2002-08-09
Effects of culture conditions on the production of polyhydroxyalkanoates by Azotobacter chroococcum H23 in media containing a high concentration of alpechín (wastewater from olive oil mills) as primary carbon source.
2002-08-07
Controlling deuterium isotope effects in comparative proteomics.
2002-08-01
Influence of yeast culture on ruminal microbial metabolism in continuous culture.
2002-08
Sensitization of trigeminal caudalis neuronal responses to intraoral acid and salt stimuli and desensitization by nicotine.
2002-08
Development of a headspace solid-phase microextraction-gas chromatography-mass spectrometry method for the identification of odour-causing volatile compounds in packaging materials.
2002-07-19
Metabolic characteristics of the faecal microflora in humans from three age groups.
2002-07
Cyproterone acetate could counteract the benefits of estradiol valerate in oophorectomized cholesterol-fed rabbits.
2002-06-26
1H and (13)C NMR spectroscopic analysis of human saliva.
2002-06
A rapid selective extraction procedure for the outer membrane protein (OmpF) from Escherichia coli.
2002-06
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
1.5 mM valeric acid is an effective chemical reagent to increase mAb production in rCHO cells.
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:17:10 GMT 2025
Edited
by admin
on Mon Mar 31 18:17:10 GMT 2025
Record UNII
HHJ036TQR0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZINC VALERATE
MI   WHO-DD  
Systematic Name English
PENTANOIC ACID ZINC SALT
Preferred Name English
ZINC VALERIANATE
Common Name English
ZINC VALERATE [MI]
Common Name English
Zinc Valerate [WHO-DD]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
209-124-1
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
PUBCHEM
68393
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
RXCUI
1546360
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY RxNorm
EPA CompTox
DTXSID00890509
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
MERCK INDEX
m11634
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY Merck Index
DAILYMED
HHJ036TQR0
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
CAS
556-38-7
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
SMS_ID
100000145791
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
FDA UNII
HHJ036TQR0
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
EVMPD
SUB124575
Created by admin on Mon Mar 31 18:17:10 GMT 2025 , Edited by admin on Mon Mar 31 18:17:10 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY