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Details

Stereochemistry ACHIRAL
Molecular Formula C5H10O2
Molecular Weight 102.1317
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VALERIC ACID

SMILES

CCCCC(O)=O

InChI

InChIKey=NQPDZGIKBAWPEJ-UHFFFAOYSA-N
InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)

HIDE SMILES / InChI

Molecular Formula C5H10O2
Molecular Weight 102.1317
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Valeric acid is a colorless, oily liquid with an unpleasant odor. It is highly corrosive and must be handled with care. Valeric acid is mainly used as a chemical intermediate to manufacture flavors and perfumes, synthetic lubricants, agricultural chemicals, and pharmaceuticals. It is also used as a flavoring aid in foods. Valeric acid is considered safe as a food additive by the World Health Organization.

Approval Year

PubMed

PubMed

TitleDatePubMed
Skin penetration and metabolism of topical glucocorticoids in reconstructed epidermis and in excised human skin.
1999 Sep
Microflora-associated characteristics in faeces from allergic and nonallergic infants.
2000 Nov
Radiolabeled cholinesterase substrates: in vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity.
2001 Feb
Characterization of partially transesterified poly(beta-hydroxyalkanoate)s by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
2001 Jul-Aug
Biotin reagents for antibody pretargeting. 5. Additional studies of biotin conjugate design to provide biotinidase stability.
2001 Jul-Aug
Intravesical valrubicin in the treatment of carcinoma in situ of the bladder.
2001 Jun
Births after transfer of zona-free blastocysts in oocyte donation cycles.
2001 Mar
Dehalogenation of dichloroethene in a contaminated soil: fatty acids and alcohols as electron donors and an apparent requirement for tetrachloroethene.
2001 Mar
Production of poly(3-hydroxybutyrateco-3-hydroxyvalerate) from cottonseed oil and valeric acid in batch culture of Raistonia sp. strain JC-64.
2001 May
Comamonas nitrativorans sp. nov., a novel denitrifier isolated from a denitrifying reactor treating landfill leachate.
2001 May
Estradiol valerate/dienogest.
2002
Comparative study of differentiation levels and valepotriate content of in vitro cultures and regenerated and wild plants of Valeriana edulis ssp.procera.
2002 Apr
Controlling deuterium isotope effects in comparative proteomics.
2002 Aug 1
A novel synthesis of (+)-biotin from L-cysteine.
2002 Aug 9
Severe hypertriglyceridemia and pancreatitis following hormone replacement prior to cryothaw transfer.
2002 Feb
Carvacrol and thymol reduce swine waste odor and pathogens: stability of oils.
2002 Jan
Ocular disposition of ganciclovir and its monoester prodrugs following intravitreal administration using microdialysis.
2002 Jun
Comparison of cryopreservation outcome with gonadotropin-releasing hormone agonists or antagonists in the collecting cycle.
2002 Mar
Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media.
2002 Mar-Apr
Geoglobus ahangari gen. nov., sp. nov., a novel hyperthermophilic archaeon capable of oxidizing organic acids and growing autotrophically on hydrogen with Fe(III) serving as the sole electron acceptor.
2002 May
Evidence for a compound in Comstock-Kellog glands modulating premating behavior in male desert locust, Schistocerca gregaria.
2002 May
Hydrogen production from wastewater by acidogenic granular sludge.
2003
Effects of hormone replacement therapy on perceptual and cognitive event-related potentials in menopausal insomnia.
2003 Apr
Activation of neurons in trigeminal caudalis by noxious oral acidic or salt stimuli is not reduced by amiloride.
2003 Apr 18
Parameter identification of thermophilic anaerobic degradation of valerate.
2003 Apr-Jun
Conformationally constrained analogues of bleomycin A5.
2003 Aug 27
Effect of method of application of a fibrolytic enzyme product on digestive processes and milk production in Holstein-Friesian cows.
2003 Feb
Enhanced biosynthesis of polyhydroxyalkanoates in a mutant strain of Rhizobium meliloti.
2003 Jan
Efficacy of betamethasone valerate foam formulation in comparison with betamethasone dipropionate lotion in the treatment of mild-to-moderate alopecia areata: a multicenter, prospective, randomized, controlled, investigator-blinded trial.
2003 Jul
Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution.
2003 Mar
Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis.
2003 Mar
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
2003 Mar 28
Left ventricular diastolic function assessment by tissue Doppler echocardiography in relation to hormonal replacement therapy in postmenopausal women with diastolic dysfunction.
2003 Mar-Apr
Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69.
2003 May
Heterogeneous acylation of flax fibers. Reaction kinetics and surface properties.
2003 May-Jun
Ruminal fermentation and bacterial protein synthesis of whole cottonseed coated with combinations of gelatinized corn starch and urea.
2003 Nov
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha.
2003 Oct 17
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.
2004 Jan 27
Sequential feeding of glucose and valerate in a fed-batch culture of Ralstonia eutropha for production of poly(hydroxybutyrate-co-hydroxyvalerate) with high 3-hydroxyvalerate fraction.
2004 Jan-Feb
Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids.
2004 Mar
Patents

Sample Use Guides

In Vitro Use Guide
1.5 mM valeric acid is an effective chemical reagent to increase mAb production in rCHO cells.
Substance Class Chemical
Created
by admin
on Tue Oct 22 02:17:42 UTC 2019
Edited
by admin
on Tue Oct 22 02:17:42 UTC 2019
Record UNII
GZK92PJM7B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VALERIC ACID
FCC   FHFI   MART.  
Systematic Name English
NSC-406833
Code English
PROPYLACETIC ACID
Systematic Name English
PENTANOIC ACID
HSDB  
Systematic Name English
1-BUTANECARBOXYLIC ACID
Systematic Name English
N-VALERIC ACID [MI]
Common Name English
VALERIC ACID [MART.]
Common Name English
PENTANOIC ACID [HSDB]
Common Name English
N-VALERIC ACID
MI  
Common Name English
VALERIC ACID [FHFI]
Common Name English
VALERIC ACID [FCC]
Common Name English
N-PENTANOIC ACID
Common Name English
VALPROIC ACID IMPURITY A [EP]
Common Name English
FEMA NO. 3101
Code English
Classification Tree Code System Code
CFR 21 CFR 172.515
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
JECFA EVALUATION VALERIC ACID
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
Code System Code Type Description
ECHA (EC/EINECS)
203-677-2
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
RXCUI
1370574
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
EPA CompTox
109-52-4
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
PUBCHEM
7991
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
MESH
C038780
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
RXCUI
1546454
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY RxNorm
MERCK INDEX
M11360
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY Merck Index
EVMPD
SUB33854
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
WIKIPEDIA
VALERIC ACID
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
CAS
109-52-4
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
HSDB
109-52-4
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> IMPURITY
UNSPECIFIED
EP
Related Record Type Details
ACTIVE MOIETY