U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H10O2
Molecular Weight 102.1317
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VALERIC ACID

SMILES

CCCCC(O)=O

InChI

InChIKey=NQPDZGIKBAWPEJ-UHFFFAOYSA-N
InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)

HIDE SMILES / InChI

Molecular Formula C5H10O2
Molecular Weight 102.1317
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Valeric acid is a colorless, oily liquid with an unpleasant odor. It is highly corrosive and must be handled with care. Valeric acid is mainly used as a chemical intermediate to manufacture flavors and perfumes, synthetic lubricants, agricultural chemicals, and pharmaceuticals. It is also used as a flavoring aid in foods. Valeric acid is considered safe as a food additive by the World Health Organization.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
[Comparative studies in man on the percutaneous absorption of diflucortolone valerate, betamethasone-17-valerate, beclomethasone dipropionate and fluocinolone acetonide].
1976
[Percutaneous absorption of diflucortolone valerate in guinea pigs and man (author's transl)].
1976
Microflora-associated characteristics in faeces from allergic and nonallergic infants.
2000 Nov
Anaerobic treatment for C and S removal in "zero-discharge" paper mills: effects of process design on S removal efficiencies.
2001
The relation of oxidized LDL autoantibodies and long-term hormone replacement therapy to ultrasonographically assessed atherosclerotic plaque quantity and severity in postmenopausal women.
2001 Aug
Effect of the liquid upflow velocity on thermophilic sulphate reduction in acidifying granular sludge reactors.
2001 Feb
Significance of substrate hydrophobicity for recognition by an oligopeptide transporter (PEPT1).
2001 Jul-Aug
Intravesical valrubicin in the treatment of carcinoma in situ of the bladder.
2001 Jun
Births after transfer of zona-free blastocysts in oocyte donation cycles.
2001 Mar
Dehalogenation of dichloroethene in a contaminated soil: fatty acids and alcohols as electron donors and an apparent requirement for tetrachloroethene.
2001 Mar
A two-choice discrimination method to assess olfactory performance in pigtailed macaques, Macaca nemestrina.
2001 Mar
Production of poly(3-hydroxybutyrateco-3-hydroxyvalerate) from cottonseed oil and valeric acid in batch culture of Raistonia sp. strain JC-64.
2001 May
Rumen microbial sequestration of [2-(13)C]acetate in cattle.
2001 Sep
Effect of casein infusion in the rumen, duodenum or both sites on factors affecting forage intake and performance of dairy cows fed red clover-grass silage.
2002 Apr
Comparative study of differentiation levels and valepotriate content of in vitro cultures and regenerated and wild plants of Valeriana edulis ssp.procera.
2002 Apr
Sensitization of trigeminal caudalis neuronal responses to intraoral acid and salt stimuli and desensitization by nicotine.
2002 Aug
Oestrogen therapy for prevention of reinfarction in postmenopausal women: a randomised placebo controlled trial.
2002 Dec 21-28
Mesophilic acidification of gelatinaceous wastewater.
2002 Feb 14
Volatile flavor components of stored nonfat dry milk.
2002 Jan 16
Metabolic characteristics of the faecal microflora in humans from three age groups.
2002 Jul
Development of a headspace solid-phase microextraction-gas chromatography-mass spectrometry method for the identification of odour-causing volatile compounds in packaging materials.
2002 Jul 19
Characterization of copolymer hydroxybutyrate/hydroxyvalerate from saponified vernonia, soybean, and "spent" frying oils.
2002 Jul-Aug
Cyproterone acetate could counteract the benefits of estradiol valerate in oophorectomized cholesterol-fed rabbits.
2002 Jul-Aug
1H and (13)C NMR spectroscopic analysis of human saliva.
2002 Jun
Ocular disposition of ganciclovir and its monoester prodrugs following intravitreal administration using microdialysis.
2002 Jun
In vitro alterations in fecal short chain fatty acids and organic anions induced by the destruction of intestinal microflora under hypotonic and aerobic conditions.
2002 Jun
Geoglobus ahangari gen. nov., sp. nov., a novel hyperthermophilic archaeon capable of oxidizing organic acids and growing autotrophically on hydrogen with Fe(III) serving as the sole electron acceptor.
2002 May
Evidence for a compound in Comstock-Kellog glands modulating premating behavior in male desert locust, Schistocerca gregaria.
2002 May
Acylated triterpenoid saponins from the stem bark of Foetidia africana.
2002 Nov
Mass production of methane from food wastes with concomitant wastewater treatment.
2002 Spring
Production of specific copolymers of polyhydroxyalkanoates from industrial waste.
2002 Spring
Production of purified polyhydroxyalkanoates (PHAs) for applications in contact with blood.
2003
Eubacterium pyruvativorans sp. nov., a novel non-saccharolytic anaerobe from the rumen that ferments pyruvate and amino acids, forms caproate and utilizes acetate and propionate.
2003 Jul
Dynamics of the anaerobic process: effects of volatile fatty acids.
2003 Jun 30
Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution.
2003 Mar
Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis.
2003 Mar
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
2003 Mar 28
Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69.
2003 May
Heterogeneous acylation of flax fibers. Reaction kinetics and surface properties.
2003 May-Jun
Synthesis, X-ray crystal structure, UV/visible linear and nonlinear (optical limiting) spectral properties of symmetrical and unsymmetrical porphyrazines with annulated 1,2,5-thiadiazole and 1,4-diamyloxybenzene moieties.
2003 Sep 5
The degradability of biodegradable plastics in aerobic and anaerobic waste landfill model reactors.
2004 Jan
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.
2004 Jan 27
Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids.
2004 Mar
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
1.5 mM valeric acid is an effective chemical reagent to increase mAb production in rCHO cells.
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:24:36 GMT 2023
Edited
by admin
on Fri Dec 15 16:24:36 GMT 2023
Record UNII
GZK92PJM7B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VALERIC ACID
FCC   FHFI   MART.  
Systematic Name English
NSC-406833
Code English
VALPROIC ACID IMPURITY A [EP IMPURITY]
Common Name English
PROPYLACETIC ACID
Systematic Name English
PENTANOIC ACID
HSDB  
Systematic Name English
1-BUTANECARBOXYLIC ACID
Systematic Name English
N-VALERIC ACID [MI]
Common Name English
VALERIC ACID [MART.]
Common Name English
PENTANOIC ACID [HSDB]
Common Name English
N-VALERIC ACID
MI  
Common Name English
VALERIC ACID [FHFI]
Common Name English
VALERIC ACID [FCC]
Common Name English
N-PENTANOIC ACID
Common Name English
FEMA NO. 3101
Code English
Classification Tree Code System Code
CFR 21 CFR 172.515
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
JECFA EVALUATION VALERIC ACID
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
Code System Code Type Description
ECHA (EC/EINECS)
203-677-2
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
RXCUI
1370574
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
JECFA MONOGRAPH
278
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
DAILYMED
GZK92PJM7B
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
EPA CompTox
DTXSID7021655
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
PUBCHEM
7991
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
CHEBI
17418
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
MESH
C038780
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
RXCUI
1546454
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY RxNorm
MERCK INDEX
m11360
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY Merck Index
DRUG BANK
DB02406
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
FDA UNII
GZK92PJM7B
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
SMS_ID
100000127757
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
EVMPD
SUB33854
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
NSC
406833
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
WIKIPEDIA
VALERIC ACID
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
CAS
109-52-4
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
HSDB
5390
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
ALANWOOD
valerate
Created by admin on Fri Dec 15 16:24:37 GMT 2023 , Edited by admin on Fri Dec 15 16:24:37 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> IMPURITY
UNSPECIFIED
CHROMATOGRAPHIC PURITY (GC)
EP
Related Record Type Details
ACTIVE MOIETY