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Details

Stereochemistry ACHIRAL
Molecular Formula C5H10O2
Molecular Weight 102.1317
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VALERIC ACID

SMILES

CCCCC(O)=O

InChI

InChIKey=NQPDZGIKBAWPEJ-UHFFFAOYSA-N
InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)

HIDE SMILES / InChI

Molecular Formula C5H10O2
Molecular Weight 102.1317
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Valeric acid is a colorless, oily liquid with an unpleasant odor. It is highly corrosive and must be handled with care. Valeric acid is mainly used as a chemical intermediate to manufacture flavors and perfumes, synthetic lubricants, agricultural chemicals, and pharmaceuticals. It is also used as a flavoring aid in foods. Valeric acid is considered safe as a food additive by the World Health Organization.

Approval Year

PubMed

PubMed

TitleDatePubMed
Influence of yeast culture on ruminal microbial metabolism in continuous culture.
2002 Aug
Sensitization of trigeminal caudalis neuronal responses to intraoral acid and salt stimuli and desensitization by nicotine.
2002 Aug
Controlling deuterium isotope effects in comparative proteomics.
2002 Aug 1
Effects of culture conditions on the production of polyhydroxyalkanoates by Azotobacter chroococcum H23 in media containing a high concentration of alpechín (wastewater from olive oil mills) as primary carbon source.
2002 Aug 7
A novel synthesis of (+)-biotin from L-cysteine.
2002 Aug 9
Oestrogen therapy for prevention of reinfarction in postmenopausal women: a randomised placebo controlled trial.
2002 Dec 21-28
Metabolic characteristics of the faecal microflora in humans from three age groups.
2002 Jul
Development of a headspace solid-phase microextraction-gas chromatography-mass spectrometry method for the identification of odour-causing volatile compounds in packaging materials.
2002 Jul 19
Characterization of copolymer hydroxybutyrate/hydroxyvalerate from saponified vernonia, soybean, and "spent" frying oils.
2002 Jul-Aug
Cyproterone acetate could counteract the benefits of estradiol valerate in oophorectomized cholesterol-fed rabbits.
2002 Jul-Aug
1H and (13)C NMR spectroscopic analysis of human saliva.
2002 Jun
A rapid selective extraction procedure for the outer membrane protein (OmpF) from Escherichia coli.
2002 Jun
Acylated triterpenoid saponins from the stem bark of Foetidia africana.
2002 Nov
Hormone replacement therapy and vigilance: double-blind, placebo-controlled EEG-mapping studies with an estrogen-progestogen combination (Climodien, Lafamme) versus estrogen alone in menopausal syndrome patients.
2002 Nov 20
Polymers for biodegradable medical devices XI. Microencapsulation studies: characterization of hydrocortisone-loaded poly-hydroxybutyrate-hydroxyvalerate microspheres.
2002 Nov-Dec
Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells.
2002 Oct 4
Production of purified polyhydroxyalkanoates (PHAs) for applications in contact with blood.
2003
Liquefaction and methanization of solid and liquid coffee wastes by two phase anaerobic digestion process.
2003
Hydrogen production from wastewater by acidogenic granular sludge.
2003
Psychophysical evaluation of responses to pleasant and mal-odour stimulation in human subjects; adaptation, dose response and gender differences.
2003 Apr
Effects of hydrochloric, valeric, and other volatile fatty acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses.
2003 Apr
Effects of hormone replacement therapy on perceptual and cognitive event-related potentials in menopausal insomnia.
2003 Apr
Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids.
2003 Apr 18
Activation of neurons in trigeminal caudalis by noxious oral acidic or salt stimuli is not reduced by amiloride.
2003 Apr 18
Parameter identification of thermophilic anaerobic degradation of valerate.
2003 Apr-Jun
Synthesis and cytotoxicity of new platinum(IV) complexes of mixed carboxylates.
2003 Aug 1
Conformationally constrained analogues of bleomycin A5.
2003 Aug 27
Effect of method of application of a fibrolytic enzyme product on digestive processes and milk production in Holstein-Friesian cows.
2003 Feb
Enhanced biosynthesis of polyhydroxyalkanoates in a mutant strain of Rhizobium meliloti.
2003 Jan
Eubacterium pyruvativorans sp. nov., a novel non-saccharolytic anaerobe from the rumen that ferments pyruvate and amino acids, forms caproate and utilizes acetate and propionate.
2003 Jul
Efficacy of betamethasone valerate foam formulation in comparison with betamethasone dipropionate lotion in the treatment of mild-to-moderate alopecia areata: a multicenter, prospective, randomized, controlled, investigator-blinded trial.
2003 Jul
Dynamics of the anaerobic process: effects of volatile fatty acids.
2003 Jun 30
Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution.
2003 Mar
Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis.
2003 Mar
Optimizing the level of wet corn gluten feed in the diet of lactating dairy cows.
2003 Mar
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
2003 Mar 28
Left ventricular diastolic function assessment by tissue Doppler echocardiography in relation to hormonal replacement therapy in postmenopausal women with diastolic dysfunction.
2003 Mar-Apr
Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69.
2003 May
[Anti-arrhythmia activity of estradiol valerate and estradiol nitrate].
2003 May-Jun
Heterogeneous acylation of flax fibers. Reaction kinetics and surface properties.
2003 May-Jun
Ruminal fermentation and bacterial protein synthesis of whole cottonseed coated with combinations of gelatinized corn starch and urea.
2003 Nov
Pelleted beet pulp substituted for high-moisture corn: 3. Effects on ruminal fermentation, pH, and microbial protein efficiency in lactating dairy cows.
2003 Nov
Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation.
2003 Nov 21
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha.
2003 Oct 17
Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate.
2003 Oct 20
Synthesis, X-ray crystal structure, UV/visible linear and nonlinear (optical limiting) spectral properties of symmetrical and unsymmetrical porphyrazines with annulated 1,2,5-thiadiazole and 1,4-diamyloxybenzene moieties.
2003 Sep 5
The degradability of biodegradable plastics in aerobic and anaerobic waste landfill model reactors.
2004 Jan
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.
2004 Jan 27
Sequential feeding of glucose and valerate in a fed-batch culture of Ralstonia eutropha for production of poly(hydroxybutyrate-co-hydroxyvalerate) with high 3-hydroxyvalerate fraction.
2004 Jan-Feb
Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids.
2004 Mar
Patents

Sample Use Guides

In Vitro Use Guide
1.5 mM valeric acid is an effective chemical reagent to increase mAb production in rCHO cells.
Substance Class Chemical
Created
by admin
on Tue Oct 22 02:17:42 UTC 2019
Edited
by admin
on Tue Oct 22 02:17:42 UTC 2019
Record UNII
GZK92PJM7B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VALERIC ACID
FCC   FHFI   MART.  
Systematic Name English
NSC-406833
Code English
PROPYLACETIC ACID
Systematic Name English
PENTANOIC ACID
HSDB  
Systematic Name English
1-BUTANECARBOXYLIC ACID
Systematic Name English
N-VALERIC ACID [MI]
Common Name English
VALERIC ACID [MART.]
Common Name English
PENTANOIC ACID [HSDB]
Common Name English
N-VALERIC ACID
MI  
Common Name English
VALERIC ACID [FHFI]
Common Name English
VALERIC ACID [FCC]
Common Name English
N-PENTANOIC ACID
Common Name English
VALPROIC ACID IMPURITY A [EP]
Common Name English
FEMA NO. 3101
Code English
Classification Tree Code System Code
CFR 21 CFR 172.515
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
JECFA EVALUATION VALERIC ACID
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
Code System Code Type Description
ECHA (EC/EINECS)
203-677-2
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
RXCUI
1370574
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
EPA CompTox
109-52-4
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
PUBCHEM
7991
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
MESH
C038780
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
RXCUI
1546454
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY RxNorm
MERCK INDEX
M11360
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY Merck Index
EVMPD
SUB33854
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
WIKIPEDIA
VALERIC ACID
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
CAS
109-52-4
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
HSDB
109-52-4
Created by admin on Tue Oct 22 02:17:43 UTC 2019 , Edited by admin on Tue Oct 22 02:17:43 UTC 2019
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> IMPURITY
UNSPECIFIED
EP
Related Record Type Details
ACTIVE MOIETY