GLUTARIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H8O4
Molecular Weight	132.1146
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CCCC(O)=O

InChI

InChIKey=JFCQEDHGNNZCLN-UHFFFAOYSA-N

InChI=1S/C5H8O4/c6-4(7)2-1-3-5(8)9/h1-3H2,(H,6,7)(H,8,9)

HIDE SMILES / InChI

Molecular Formula	C5H8O4
Molecular Weight	132.1146
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Adult onset glutaric aciduria type I presenting with a leukoencephalopathy.	2003-04-22	12707462
Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme.	2003-04-08	12667063
Late-onset form of beta-electron transfer flavoprotein deficiency.	2003-04	12706375
Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.	2003-04	12488248
Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells.	2003-03	12606766
Glutaric acid induces oxidative stress in brain of young rats.	2003-02-21	12573524
Effects of tallow in diets based on corn silage or alfalfa silage on digestion and nutrient use by lactating dairy cows.	2003-02	12647966
Glutaric aciduria I: creatine supplementation restores creatinephosphate levels in mixed cortex cells from rat incubated with 3-hydroxyglutarate.	2003-02	12618082
Escherichia coli O157:H7 populations in sheep can be reduced by chlorate supplementation.	2003-02	12597476
Atmospheric pressure mass spectrometry: a new analytical chemical characterization method for dissolved organic matter in rainwater.	2003-01-01	12542301
Intraruminal propionate supplementation modifies hindlimb energy metabolism without changing the splanchnic release of glucose in growing lambs.	2003-01	12568663
Adult onset glutaric aciduria type I presenting with a leukoencephalopathy.	2002-12-10	12473778
Cloning of the pig renal organic anion transporter 1 (pOAT1).	2002-12	12628298
Evaluation of finishing performance, carcass characteristics, acid-resistant E. coli and total coliforms from steers fed combinations of wet corn gluten feed and steam-flaked corn.	2002-12	12542174
Effects of a monensin controlled-release capsule or premix on attenuation of subacute ruminal acidosis in dairy cows.	2002-12	12512618
Evaluation of filter paper collection of urine samples for detection and measurement of organic acidurias by capillary electrophoresis.	2002-11-15	12383482
Cancer chemopreventive effect of quassinoid derivatives. Introduction of side chain to shinjulactone C for enhancement of inhibitory effect on Epstein-Barr virus activation.	2002-11-08	12142078
New antioxidant hydroquinone derivatives from the algicolous marine fungus Acremonium sp.	2002-11	12444684
New partially oxidized 1-D platinum chain complexes consisting of carboxylate-bridged cis-diammineplatinum dimer cations.	2002-10-16	12371836
Glutaric acidemia type II: gene structure and mutations of the electron transfer flavoprotein:ubiquinone oxidoreductase (ETF:QO) gene.	2002-10-03	12359134
Glutaric aciduria type III: a distinctive non-disease?	2002-10	12555941
White matter disease in cerebral organic acid disorders: clinical implications and suggested pathomechanisms.	2002-10	12536363
Effects of Saccharomyces cerevisiae culture and Saccharomyces cerevisiae live cells on in vitro mixed ruminal microorganism fermentation.	2002-10	12416814
Antitumor activities of conjugates of mitomycin C with estradiol benzoate and estradiol via glutaric acid in suspension dosage form.	2002-10	12392099
Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1.	2002-10	12237339
Ratiometric probes for hydrogencarbonate analysis in intracellular or extracellular environments using europium luminescence.	2002-09-07	12271679
Renal organic anion transport system: a mechanism for the basolateral uptake of mercury-thiol conjugates along the pars recta of the proximal tubule.	2002-08-01	12183103
Novel mutation and prenatal sonographic findings of glutaric aciduria (type I) in two Taiwanese families.	2002-08	12210585
Isomer separation of hyperbranched polyesteramides with gas-phase H/D exchange and a novel MS(n) approach: DoDIP.	2002-08	12203673
Comparison of the pharmacological profile of an olivacine derivative and a potential prodrug.	2002-08	12172972
By-product feeds for meat goats: effects on digestibility, ruminal environment, and carcass characteristics.	2002-07	12162642
NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria.	2002-07	12153528
Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice.	2002-07	12065749
Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors.	2002-06-06	12036373
The effects of organic species on the hygroscopic behaviors of inorganic aerosols.	2002-06-01	12075799
Melaminium glutarate monohydrate.	2002-06	12050435
Chronic treatment with glutaric acid induces partial tolerance to excitotoxicity in neuronal cultures from chick embryo telencephalons.	2002-05-15	11992468
Prediction of ruminal pH from pasture-based diets.	2002-05	12086063
Glutaric aciduria type I diagnosed after poliovirus immunization: magnetic resonance findings.	2002-05	12057806
Utilization of Bt corn residues by grazing beef steers and Bt corn silage and grain by growing beef cattle and lactating dairy cows.	2002-05	12019625
[Glutaric aciduria type 2].	2002-04	12013989
[Electron transfer flavoprotein in mitochondria].	2002-04	12013830
Effect of supplemental tallow on performance of dairy cows fed diets with different corn silage:alfalfa silage ratios.	2002-03	11949868
Effects of restricted and ad libitum intake of diets containing wheat middlings on site and extent of digestion in steers.	2002-03	11890419
Glutaric aciduria type 1 and nonaccidental head injury.	2002-03	11875161
A 9-month-old baby with subdural hematomas, retinal hemorrhages, and developmental delay.	2002-02	11862140
[Organic acid disorders: cerebral organic acidemia].	2002	12483853
Molecular characterization of the renal organic anion transporter 1.	2002	12139402
Biochemical and molecular diagnosis of glutaric aciduria type 1 in a black South African male child: case report.	2001-12	12199454
[Simultaneous determination of 11 organic acids in fruit juice by ion exclusion chromatography].	2001-05	12541818

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:46:02 GMT 2025` Edited by `admin` on `Mon Mar 31 17:46:02 GMT 2025`
Record UNII	H849F7N00B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLUTARIC ACID

Official Name

English

NSC-9238

Preferred Name

English

PENTANEDIOIC ACID

Systematic Name

English

GLUTARIC ACID [MI]

Common Name

English

GLUTARIC ACID [HSDB]

Common Name

English

1,3-PENTANEDIOIC ACID (RIFM)

Common Name

English

1,3-PROPANEDICARBOXYLIC ACID

Systematic Name

English

ADIPIC ACID IMPURITY A [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

LOINC

27301-1