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Details

Stereochemistry ACHIRAL
Molecular Formula Mn
Molecular Weight 54.938
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of MANGANOUS CATION

SMILES

[Mn++]

InChI

InChIKey=WAEMQWOKJMHJLA-UHFFFAOYSA-N
InChI=1S/Mn/q+2

HIDE SMILES / InChI

Molecular Formula Mn
Molecular Weight 54.938
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Manganese Difluoride is a light pink crystalline solid composed of manganese and fluoride with the formula MnF2. Manganese Difluoride is made by treating manganese and diverse compounds of manganese(II) in hydrofluoric acid. Manganese Difluoride is used in the manufacture of special kinds of glass and lasers.

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Manganese is used for prevention and treatment of manganese deficiency, a condition in which the body doesn’t have enough manganese.
Primary
Unknown

Approved Use

Manganese is used for weak bones (osteoporosis).
Palliative
Unknown

Approved Use

Early research suggests that taking manganese along with calcium helps improve symptoms of PMS, including pain, crying, loneliness, anxiety, restlessness, irritability, mood swings, depression, and tension.
Curative
MANGANESE SULFATE

Approved Use

Manganese Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for Total Parenteral Nutrition (TPN). Administration helps to maintain plasma levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
Primary
MANGANESE SULFATE

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Cytochrome oxidase determination using a manganese citrate complex.
1970
Metabolism of l-Tyrosine to 4-Hydroxybenzaldehyde and 3-Bromo-4-Hydroxybenzaldehyde by Chloroplast-containing Fractions of Odonthalia floccosa (Esp.) Falk.
1979 Dec
Effect of fluoride on copper, manganese and zinc in bone and kidney.
1981 Mar
Effect of quantity and route of administration of manganese monoxide on feed intake and serum manganese in ruminants.
1985 Feb
Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure.
1993 Jul
Dietary calcium and manganese effects on menstrual cycle symptoms.
1993 May
Manganese citrate chemistry: syntheses, spectroscopic studies, and structural characterizations of novel mononuclear, water-soluble manganese citrate complexes.
2000 Sep 4
Equilibrium and kinetics studies of reactions of manganese acetate, cobalt acetate, and bromide salts in acetic acid solutions.
2001 Jun 18
Differential ability of transition metals to induce pulmonary inflammation.
2001 Nov 15
Tetraaqua(1,10-phenanthroline-kappa(2)N,N')manganese(II) sulfate dihydrate.
2002 Jul
Bi- and poly-metallic cyanide-bridged complexes of the redox-active cyanomanganese nitrosyl unit [Mn(CN)(PR3)(NO)(eta-C5H4Me)].
2004 Feb 21
Decreased expression of inflammation-related genes following inhalation exposure to manganese.
2006 May
Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese.
2006 Summer
Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity.
2007 Jun
Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics.
2014 May
Controlled Synthesis of Hollow Manganese Oxide Nanocrystals.
2016 Feb
Yolk-Shell MnO@ZnMn(2) O(4) /N-C Nanorods Derived from α-MnO(2) /ZIF-8 as Anode Materials for Lithium Ion Batteries.
2016 Oct
Top-Down Strategy to Synthesize Mesoporous Dual Carbon Armored MnO Nanoparticles for Lithium-Ion Battery Anodes.
2017 Apr 12
Intramolecular Aminoalkoxylation of Unfunctionalized Olefins via Intramolecular Iodoamination and Aziridinium Ion Ring-Opening Sequence.
2017 Apr 7
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Curator's Comment: In vitro cytotoxicity of manganese oxide (MnO) using live/dead cell assay, lactate dehydrogenase assay, and reactive oxygen species detection with variation of the concentration of nanoparticles (5-500 ug/ml), incubation time (18-96 h), and different human cell lines (lung adenocarcinoma, breast cancer cells, and glioblastoma cells) was studied. The cytotoxic effect was negligible for 18 h incubation even at highest concentration of 500 ug/ml MnO nanoparticle.
Unknown
Substance Class Chemical
Created
by admin
on Wed Jul 05 23:58:02 UTC 2023
Edited
by admin
on Wed Jul 05 23:58:02 UTC 2023
Record UNII
H6EP7W5457
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MANGANOUS CATION
Common Name English
MANGANESE, ION (MN2+)
Common Name English
MANGANESE(II) ION
Common Name English
MANGANESE(II)
Systematic Name English
MANGANESE CATION (MN2+)
Common Name English
MANGANESE ION(2+)
Common Name English
MANGANESE CATION (2+)
Common Name English
MANGANESE DICATION
Common Name English
MANGANESE(2+)
Systematic Name English
Classification Tree Code System Code
NDF-RT N0000180184
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
NDF-RT N0000175862
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID00167687
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
CHEBI
29035
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
RXCUI
1546272
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY RxNorm
DAILYMED
H6EP7W5457
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
SMS_ID
100000179980
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
NCI_THESAURUS
C68267
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
FDA UNII
H6EP7W5457
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
CAS
16397-91-4
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
PUBCHEM
27854
Created by admin on Wed Jul 05 23:58:03 UTC 2023 , Edited by admin on Wed Jul 05 23:58:03 UTC 2023
PRIMARY
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