Clesitamig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 14:39:08 GMT 2025` Edited by `admin` on `Wed Apr 02 14:39:08 GMT 2025`
Protein Type	TRISPECIFIC ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	H57D6SR4FE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin, anti-(human notch ligand DLL3 extracellular domain) (human-Oryctolagus cuniculus monoclonal D08410053H0118/D084101L0000 light chain variable region) fusion protein with peptide linker (SS) fusion protein with immunoglobulin (human ?1-chai

Preferred Name

English

Clesitamig

Official Name

English

fused heavy chain V-kappa-G4CH1-G1h anti-DLL3-H-gamma1 anti-CD3/TNFRSF9 (1-676) [V-kappa-G4CH1-G1h anti-DLL3 humanized (1-215) [V-KAPPA (Homo sapiens IGKV1-33*01 (76.3%) -IGKJ4*01 (100%), CDR-IMGT [8.3.10] (27-34.52-54.91-100)) (1-110) -2-mer diseryl (11

Common Name

English

immunoglobulin [(V-kappa-G4CH1-G1h-H-gamma1_L-kappa)_Lkappa)]_(H-gamma1_L-kappa), anti-[Homo sapiens DLL3 (delta-like ligand 3, delta like canonical Notch ligand 3)], anti-[Homo sapiens CD3/TNFRSF9 (TNF receptor superfamily member 9, 4-1BB, T cell antige

Common Name

English

clesitamig [INN]

Common Name

English

Code System Code Type Description

INN

13237