Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C29H27N7O4S |
| Molecular Weight | 569.634 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC(NC2=C3C=C(C=CC3=NC=N2)C4=CC=C(CNCCS(C)(=O)=O)O4)=CC=C1OC5=CC6=NC=NN6C=C5
InChI
InChIKey=QVMNYGOVNWWFKF-UHFFFAOYSA-N
InChI=1S/C29H27N7O4S/c1-19-13-21(4-7-26(19)39-22-9-11-36-28(15-22)32-18-34-36)35-29-24-14-20(3-6-25(24)31-17-33-29)27-8-5-23(40-27)16-30-10-12-41(2,37)38/h3-9,11,13-15,17-18,30H,10,12,16H2,1-2H3,(H,31,33,35)
| Molecular Formula | C29H27N7O4S |
| Molecular Weight | 569.634 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
N-(4-((1,2,4)TRIAZOLO(1,5-A)PYRIDIN-7-YLOXY)-3-METHYLPHENYL)-6-(5-(((2-(METHYLSULFONYL)ETHYL)AMINO)METHYL)FURAN-2-YL)QUINAZOLIN-4-AMINE is an inhibitor of ErbB family of tyrosine kinases which was developed by Array Biopharma for the treatment of hyperproliferative diseases (cancer). The compound is marketed as Arry-380 analog, and should not be confused with Arry-380 (Tucatinib), which has a different, albeit largely similar structure.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:33:30 GMT 2023
by
admin
on
Sat Dec 16 05:33:30 GMT 2023
|
| Record UNII |
H32S1659ED
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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H32S1659ED
Created by
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42598643
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937265-83-3
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admin on Sat Dec 16 05:33:31 GMT 2023 , Edited by admin on Sat Dec 16 05:33:31 GMT 2023
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DTXSID00239555
Created by
admin on Sat Dec 16 05:33:31 GMT 2023 , Edited by admin on Sat Dec 16 05:33:31 GMT 2023
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