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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H16FN2O14P3
Molecular Weight 500.1592
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLEVUDINE TRIPHOSPHATE

SMILES

Cc1cn([C@]2([H])[C@@]([H])([C@]([H])([C@]([H])(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)O)F)c(=O)nc1O

InChI

InChIKey=RUKRVHYQIIURNV-XQXXSGGOSA-N
InChI=1S/C10H16FN2O14P3/c1-4-2-13(10(16)12-8(4)15)9-6(11)7(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-7,9,14H,3H2,1H3,(H,20,21)(H,22,23)(H,12,15,16)(H2,17,18,19)/t5-,6+,7-,9-/m0/s1

HIDE SMILES / InChI

Molecular Formula C10H16FN2O14P3
Molecular Weight 500.1592
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase.
2003 Jan
Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine.
2013 Sep
Substance Class Chemical
Created
by admin
on Sat Jun 26 03:49:43 UTC 2021
Edited
by admin
on Sat Jun 26 03:49:43 UTC 2021
Record UNII
GYY7PAS72J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLEVUDINE TRIPHOSPHATE
MI  
Common Name English
2,4(1H,3H)-PYRIMIDINEDIONE, 1-(2-DEOXY-2-FLUORO-5-O-(HYDROXY((HYDROXY(PHOSPHONOOXY)PHOSPHINYL)OXY)PHOSPHINYL)-.BETA.-L-ARABINOFURANOSYL)-5-METHYL-
Common Name English
L-FMAU-TP
Common Name English
CLEVUDINE TRIPHOSPHATE [MI]
Common Name English
Code System Code Type Description
CAS
174625-00-4
Created by admin on Sat Jun 26 03:49:43 UTC 2021 , Edited by admin on Sat Jun 26 03:49:43 UTC 2021
PRIMARY
MERCK INDEX
M3621
Created by admin on Sat Jun 26 03:49:43 UTC 2021 , Edited by admin on Sat Jun 26 03:49:43 UTC 2021
PRIMARY Merck Index
PUBCHEM
503024
Created by admin on Sat Jun 26 03:49:43 UTC 2021 , Edited by admin on Sat Jun 26 03:49:43 UTC 2021
PRIMARY
FDA UNII
GYY7PAS72J
Created by admin on Sat Jun 26 03:49:43 UTC 2021 , Edited by admin on Sat Jun 26 03:49:43 UTC 2021
PRIMARY
Related Record Type Details
PRODRUG -> METABOLITE ACTIVE