U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:00:24 GMT 2023
Edited
by admin
on Sat Dec 16 15:00:24 GMT 2023
Protein Type FC FUSION PROTEIN
Protein Sub Type BISPECIFIC T CELL ENGAGER
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
GLR3JG8TZU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PAVURUTAMAB
INN   USAN  
Official Name English
PAVURUTAMAB [USAN]
Common Name English
AMG701
Code English
ANTI-BCMA X ANTI-CD3 BITE AMG 701
Common Name English
AMG-701
Code English
IMMUNOGLOBULIN SCFV-SCFV-SCFC, ANTI-(HOMO SAPIENS TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17 (B-CELL MATURATION PROTEIN, CD269_ANTIGEN)) TNR17 AND ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN (T-CELL SURFACE ANTIGEN T3/LEU-4
Common Name English
BCMA/CD3-DIRECTED BISPECIFIC T-CELL ENGAGER ANTIBODY AMG 701
Common Name English
IMMUNOGLOBULIN, ANTI-(HUMAN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY PROTEIN TNFRSF17) (HUMAN MONOCLONAL BRA-HWZV 1 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUM
Common Name English
Pavurutamab [WHO-DD]
Common Name English
pavurutamab [INN]
Common Name English
ANTI-BCMA X ANTI-CD3 BITE (BISPECIFIC T CELL ENGAGER) ANTIBODY CONSTRUCT
Common Name English
ANTI-BCMA/CD3 BITE ANTIBODY AMG 701
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 669618
Created by admin on Sat Dec 16 15:00:24 GMT 2023 , Edited by admin on Sat Dec 16 15:00:24 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C147028
Created by admin on Sat Dec 16 15:00:24 GMT 2023 , Edited by admin on Sat Dec 16 15:00:24 GMT 2023
PRIMARY
FDA UNII
GLR3JG8TZU
Created by admin on Sat Dec 16 15:00:24 GMT 2023 , Edited by admin on Sat Dec 16 15:00:24 GMT 2023
PRIMARY
USAN
HI-217
Created by admin on Sat Dec 16 15:00:24 GMT 2023 , Edited by admin on Sat Dec 16 15:00:24 GMT 2023
PRIMARY
CAS
2250292-39-6
Created by admin on Sat Dec 16 15:00:24 GMT 2023 , Edited by admin on Sat Dec 16 15:00:24 GMT 2023
PRIMARY
CAS
2298375-18-3
Created by admin on Sat Dec 16 15:00:24 GMT 2023 , Edited by admin on Sat Dec 16 15:00:24 GMT 2023
SUPERSEDED
INN
11290
Created by admin on Sat Dec 16 15:00:24 GMT 2023 , Edited by admin on Sat Dec 16 15:00:24 GMT 2023
PRIMARY
From To
1_44 1_236
1_22 1_96
1_159 1_224
1_271 1_347
1_411 1_479
1_508 1_765
1_511 1_768
1_543 1_603
1_574 1_584
1_800 1_860
1_649 1_707
1_906 1_964
1_831 1_841
Related Record Type Details
TARGET -> ACTIVATOR
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL