RAMIFENAZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NC1=C(C)N(C)N(C1=O)C2=CC=CC=C2

InChI

InChIKey=XOZLRRYPUKAKMU-UHFFFAOYSA-N

InChI=1S/C14H19N3O/c1-10(2)15-13-11(3)16(4)17(14(13)18)12-8-6-5-7-9-12/h5-10,15H,1-4H3

HIDE SMILES / InChI

Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/21684706 | https://link.springer.com/article/10.1007%2FBF01971489

Ramifenazone is pyrazolone derivative with analgesic, antipyretic, and anti-inflammatory activity. In preclinical studies, Ramifenazone shows potent inhibition of prostaglandin production, carrageenan edema, and yeast fever.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Analysis of three metabolite residues of dipyrone in bovine muscle and pork muscle using high performance liquid chromatography].	2007 Nov	18257301
Analytical strategy for the confirmatory analysis of the non-steroidal anti-inflammatory drugs firocoxib, propyphenazone, ramifenazone and piroxicam in bovine plasma by liquid chromatography tandem mass spectrometry.	2011 Sep 10	21684706

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:35:31 UTC 2023` Edited by `admin` on `Fri Dec 15 15:35:31 UTC 2023`
Record UNII	GKH2KOV2RF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RAMIFENAZONE

Official Name

English

ISOPROPYLAMINOPHENAZONE

Systematic Name

English

Ramifenazone [WHO-DD]

Common Name

English

ramifenazone [INN]

Common Name

English

1-PHENYL-2,3-DIMETHYL-4-ISOPROPYLAMINOPYRAZOLONE

Systematic Name

English

NSC-758621

Code

English

RAMIFENAZONE [MART.]

Common Name

English

1-PHENYL-2,3-DIMETHYL-4-(ISOPROPYLAMINO)-2-PYRAZOLIN-5-ONE

Systematic Name

English

ISOPROPYLAMINOANTIPYRINE

Common Name

English

RAMIFENAZONE [MI]

Common Name

English

3H-PYRAZOL-3-ONE, 1,2-DIHYDRO-1,5-DIMETHYL-4-((1-METHYLETHYL)AMINO)-2-PHENYL-

Systematic Name

English

ISOPYRINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257