RAMIFENAZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NC1=C(C)N(C)N(C1=O)C2=CC=CC=C2

InChI

InChIKey=XOZLRRYPUKAKMU-UHFFFAOYSA-N

InChI=1S/C14H19N3O/c1-10(2)15-13-11(3)16(4)17(14(13)18)12-8-6-5-7-9-12/h5-10,15H,1-4H3

HIDE SMILES / InChI

Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/21684706 | https://link.springer.com/article/10.1007%2FBF01971489

Ramifenazone is pyrazolone derivative with analgesic, antipyretic, and anti-inflammatory activity. In preclinical studies, Ramifenazone shows potent inhibition of prostaglandin production, carrageenan edema, and yeast fever.

Originator

Approval Year

PubMed

Title	Date	PubMed
Analytical strategy for the confirmatory analysis of the non-steroidal anti-inflammatory drugs firocoxib, propyphenazone, ramifenazone and piroxicam in bovine plasma by liquid chromatography tandem mass spectrometry.	2011-09-10	21684706
[Analysis of three metabolite residues of dipyrone in bovine muscle and pork muscle using high performance liquid chromatography].	2007-11	18257301

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:02:15 GMT 2025` Edited by `admin` on `Mon Mar 31 18:02:15 GMT 2025`
Record UNII	GKH2KOV2RF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ISOPROPYLAMINOANTIPYRINE

Preferred Name

English

RAMIFENAZONE

Official Name

English

ISOPROPYLAMINOPHENAZONE

Systematic Name

English

Ramifenazone [WHO-DD]

Common Name

English

ramifenazone [INN]

Common Name

English

1-PHENYL-2,3-DIMETHYL-4-ISOPROPYLAMINOPYRAZOLONE

Systematic Name

English

NSC-758621

Code

English

RAMIFENAZONE [MART.]

Common Name

English

1-PHENYL-2,3-DIMETHYL-4-(ISOPROPYLAMINO)-2-PYRAZOLIN-5-ONE

Systematic Name

English

RAMIFENAZONE [MI]

Common Name

English

3H-PYRAZOL-3-ONE, 1,2-DIHYDRO-1,5-DIMETHYL-4-((1-METHYLETHYL)AMINO)-2-PHENYL-

Systematic Name

English

ISOPYRINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257