RAMIFENAZONE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H19N3O.ClH
Molecular Weight	281.781
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC(C)NC1=C(C)N(C)N(C1=O)C2=CC=CC=C2

InChI

InChIKey=WJPVTNJDDFIBKU-UHFFFAOYSA-N

InChI=1S/C14H19N3O.ClH/c1-10(2)15-13-11(3)16(4)17(14(13)18)12-8-6-5-7-9-12;/h5-10,15H,1-4H3;1H

HIDE SMILES / InChI

Molecular Formula	C14H19N3O
Molecular Weight	245.3202
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/21684706 | https://link.springer.com/article/10.1007%2FBF01971489

Ramifenazone is pyrazolone derivative with analgesic, antipyretic, and anti-inflammatory activity. In preclinical studies, Ramifenazone shows potent inhibition of prostaglandin production, carrageenan edema, and yeast fever.

Originator

Approval Year

PubMed

Title	Date	PubMed
Analytical strategy for the confirmatory analysis of the non-steroidal anti-inflammatory drugs firocoxib, propyphenazone, ramifenazone and piroxicam in bovine plasma by liquid chromatography tandem mass spectrometry.	2011-09-10	21684706
[Analysis of three metabolite residues of dipyrone in bovine muscle and pork muscle using high performance liquid chromatography].	2007-11	18257301

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:24:33 GMT 2025` Edited by `admin` on `Mon Mar 31 23:24:33 GMT 2025`
Record UNII	182MZB7ZV8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RAMIFENAZONE HYDROCHLORIDE

Common Name

English

ISOPYRINE HYDROCHLORIDE

Preferred Name

English

Ramifenazone hydrochloride [WHO-DD]

Common Name

English

ISOPROPYLAMINOPHENAZONE HYDROCHLORIDE

Systematic Name

English

4-(ISOPROPYLAMINO)PHENAZONE HYDROCHLORIDE

Systematic Name

English

3H-PYRAZOL-3-ONE, 1,2-DIHYDRO-1,5-DIMETHYL-4-((1-METHYLETHYL)AMINO)-2-PHENYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

SMS_ID

100000077568