U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C19H21NO2
Molecular Weight 295.3763
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BELOXEPIN

SMILES

Cc1cccc2[C@]3([H])CN(C)CC[C@@]3(c4ccccc4Oc12)O

InChI

InChIKey=RPMDQAYGQBREBS-LPHOPBHVSA-N
InChI=1S/C19H21NO2/c1-13-6-5-7-14-16-12-20(2)11-10-19(16,21)15-8-3-4-9-17(15)22-18(13)14/h3-9,16,21H,10-12H2,1-2H3/t16-,19-/m0/s1

HIDE SMILES / InChI

Molecular Formula C19H21NO2
Molecular Weight 295.3763
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Beloxepin (or ADL6906), a novel dual norepinephrine reuptake inhibitor and serotonin receptor antagonist, was investigated for the treatment of the pain and Major depressive disorder, but these studies were discontinued.

Approval Year

Sample Use Guides

ADL6906 (beloxepin) administered orally twice daily over 10 days in healthy volunteers
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Jun 26 03:57:13 UTC 2021
Edited
by admin
on Sat Jun 26 03:57:13 UTC 2021
Record UNII
G905IN29U4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BELOXEPIN
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
BELOXEPIN [WHO-DD]
Common Name English
BELOXEPIN [INN]
Common Name English
BELOXEPIN [USAN]
Common Name English
ORG-4428
Code English
ADL6906
Code English
ORG 4428
Code English
ADL-6906
Code English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
Code System Code Type Description
EVMPD
SUB05689MIG
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
PRIMARY
NCI_THESAURUS
C78007
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
PRIMARY
PUBCHEM
166560
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
PRIMARY
INN
7491
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
PRIMARY
CAS
135928-30-2
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
PRIMARY
ChEMBL
CHEMBL2104008
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
PRIMARY
FDA UNII
G905IN29U4
Created by admin on Sat Jun 26 03:57:13 UTC 2021 , Edited by admin on Sat Jun 26 03:57:13 UTC 2021
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY