BELOXEPIN

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H21NO2
Molecular Weight	295.3763
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cc1cccc2[C@]3([H])CN(C)CC[C@@]3(c4ccccc4Oc12)O

InChI

InChIKey=RPMDQAYGQBREBS-LPHOPBHVSA-N

InChI=1S/C19H21NO2/c1-13-6-5-7-14-16-12-20(2)11-10-19(16,21)15-8-3-4-9-17(15)22-18(13)14/h3-9,16,21H,10-12H2,1-2H3/t16-,19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C19H21NO2
Molecular Weight	295.3763
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.news-medical.net/news/20101111/Adolor-receives-US-Patent-for-beloxepin-to-treat-pain.aspx | https://www.jpain.org/article/S1526-5900(11)00393-2/pdf | https://adisinsight.springer.com/drugs/800001334

Beloxepin (or ADL6906), a novel dual norepinephrine reuptake inhibitor and serotonin receptor antagonist, was investigated for the treatment of the pain and Major depressive disorder, but these studies were discontinued.

Originator

Approval Year

Sample Use Guides

In Vivo Use Guide

ADL6906 (beloxepin) administered orally twice daily over 10 days in healthy volunteers

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Jun 26 03:57:13 UTC 2021` Edited by `admin` on `Sat Jun 26 03:57:13 UTC 2021`
Record UNII	G905IN29U4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BELOXEPIN

Official Name

English

BELOXEPIN [WHO-DD]

Common Name

English

BELOXEPIN [INN]

Common Name

English

BELOXEPIN [USAN]

Common Name

English

ORG-4428

Code

English

ADL6906

Code

English

ORG 4428

Code

English

ADL-6906

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C265