Details
Stereochemistry | ACHIRAL |
Molecular Formula | C22H32N6 |
Molecular Weight | 380.5297 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCN(CCC)C1=CC(C)=NC2=C(C(C)=NN12)C3=C(C)C=C(N=C3)N(C)C
InChI
InChIKey=ANNRUWYFVIGKHA-UHFFFAOYSA-N
InChI=1S/C22H32N6/c1-8-10-27(11-9-2)20-13-16(4)24-22-21(17(5)25-28(20)22)18-14-23-19(26(6)7)12-15(18)3/h12-14H,8-11H2,1-7H3
Molecular Formula | C22H32N6 |
Molecular Weight | 380.5297 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL1800 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15341493 |
50.0 nM [IC50] |
PubMed
Title | Date | PubMed |
---|---|---|
Analysis of the hormone-binding domain of steroid receptors using chimeras generated by homologous recombination. | 2005 Aug 15 |
|
Lithium, but not fluoxetine or the corticotropin-releasing factor receptor 1 receptor antagonist R121919, increases cell proliferation in the adult dentate gyrus. | 2011 Apr |
|
Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist. | 2011 Jun 23 |
|
Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. | 2013 Mar 1 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 04:36:08 GMT 2023
by
admin
on
Sat Dec 16 04:36:08 GMT 2023
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Record UNII |
G82N555U1N
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Record Status |
Validated (UNII)
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Record Version |
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DTXSID00173162
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195055-03-9
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G82N555U1N
Created by
admin on Sat Dec 16 04:36:08 GMT 2023 , Edited by admin on Sat Dec 16 04:36:08 GMT 2023
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Related Record | Type | Details | ||
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ACTIVE MOIETY |