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Details

Stereochemistry RACEMIC
Molecular Formula C14H14O2
Molecular Weight 214.2598
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENYLETHYL RESORCINOL

SMILES

CC(C1=CC=CC=C1)C2=C(O)C=C(O)C=C2

InChI

InChIKey=PQSXNIMHIHYFEE-UHFFFAOYSA-N
InChI=1S/C14H14O2/c1-10(11-5-3-2-4-6-11)13-8-7-12(15)9-14(13)16/h2-10,15-16H,1H3

HIDE SMILES / InChI

Molecular Formula C14H14O2
Molecular Weight 214.2598
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Phenylethyl resorcinol (4-(1-Phenylethyl) 1,3-benzenediol) also known as SymWhite 377, a hydroxy‐stilbene derivative, is a potent, stable and safe skin lightener. It exerts tyrosinase and melanin synthesis inhibitory activity. Anti-melanogenic activity of phenylethyl resorcinol is mediated by activation of p44/42 MAPK. The Chinese State Food and Drug Administration (SFDA) has approved SymWhite 377, a skin brightening active from supplier Symrise, as an ingredient for cosmetic applications.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
0.5% dosage
Route of Administration: Transdermal
Substance Class Chemical
Record UNII
G37UFG162O
Record Status Validated (UNII)
Record Version