U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Possibly Marketed Outside US
First approved in 2011
Source:
PIGMENT by G.S. COSMECEUTICAL USA, INC.
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Phenylethyl resorcinol (4-(1-Phenylethyl) 1,3-benzenediol) also known as SymWhite 377, a hydroxy‐stilbene derivative, is a potent, stable and safe skin lightener. It exerts tyrosinase and melanin synthesis inhibitory activity. Anti-melanogenic activity of phenylethyl resorcinol is mediated by activation of p44/42 MAPK. The Chinese State Food and Drug Administration (SFDA) has approved SymWhite 377, a skin brightening active from supplier Symrise, as an ingredient for cosmetic applications.