Adalimumab Fosimdesonide

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:02:46 UTC 2023` Edited by `admin` on `Sat Dec 16 15:02:46 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	FWC6IWT3EH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Adalimumab Fosimdesonide

Official Name

English

adalimumab fosimdesonide [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens TNF (tumor necrosis factor (TNF) superfamily member 2, TNFSF2, TNF-alpha, TNFA)], Homo sapiens monoclonal antibody, conjugated to a derivative of the glucocorticoid receptor modulator (GRM) desonide (24)(12) vi

Common Name

English

gamma1 heavy chain Homo sapiens (1-450) [VH(Homo sapiens IGHV3-9*01 (93.9%) -(IGHD) -IGHJ4*01 (92.9%)) CDR-IMGT [8.8.14] (26-33.51-58.97-110) (1-121) -Homo sapiens IGHG1*01 (100%)G1m17,1 (CH1 K120 (218) (122-219), hinge 1-15(220-234), CH2 (235-344), CH3

Common Name

English

Immunoglobulin G1, anti-(human tumor necrosis factor) (human monoclonal D2E7 heavy chain), complex with human monoclonal D2E7 light chain, dimer, 214′′,214′′′,224,224′-tetrakis(thioether) with N-(2-mercaptoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C190447

Created by admin on Sat Dec 16 15:02:46 UTC 2023 , Edited by admin on Sat Dec 16 15:02:46 UTC 2023

PRIMARY

INN

11661

Created by admin on Sat Dec 16 15:02:46 UTC 2023 , Edited by admin on Sat Dec 16 15:02:46 UTC 2023

PRIMARY

FDA UNII

FWC6IWT3EH

Created by admin on Sat Dec 16 15:02:46 UTC 2023 , Edited by admin on Sat Dec 16 15:02:46 UTC 2023

PRIMARY

CAS

2402772-93-2

Created by admin on Sat Dec 16 15:02:46 UTC 2023 , Edited by admin on Sat Dec 16 15:02:46 UTC 2023

PRIMARY

From	To
1_22	1_96
1_148	1_204
1_224	3_214
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429
2_22	2_96
2_148	2_204
2_224	4_214
2_265	2_325
2_371	2_429
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					FYS6T7F842

ADALIMUMAB

PARENT -> CONJUGATE

Amount:


					FZW85LW99M

GLUCOCORTICOID RECEPTOR

TARGET->MODULATOR

Amount:


					4TVX2I407K

TUMOR NECROSIS FACTOR-.ALPHA. HUMAN (PLASMA DERIVED, SOLUBLE FORM)

TARGET -> INHIBITOR

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:SEQUENCE	CHEMICAL
Molecular Formula	CHEMICAL