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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 03:16:37 GMT 2025
Edited
by admin
on Wed Apr 02 03:16:37 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
FWC6IWT3EH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Adalimumab Fosimdesonide
INN  
Official Name English
ABBV-154
Preferred Name English
ADALIMUMAB FOSIMDESONIDE [USAN]
Common Name English
adalimumab fosimdesonide [INN]
Common Name English
immunoglobulin G1-kappa, anti-[Homo sapiens TNF (tumor necrosis factor (TNF) superfamily member 2, TNFSF2, TNF-alpha, TNFA)], Homo sapiens monoclonal antibody, conjugated to a derivative of the glucocorticoid receptor modulator (GRM) desonide (24)(12) vi
Common Name English
gamma1 heavy chain Homo sapiens (1-450) [VH(Homo sapiens IGHV3-9*01 (93.9%) -(IGHD) -IGHJ4*01 (92.9%)) CDR-IMGT [8.8.14] (26-33.51-58.97-110) (1-121) -Homo sapiens IGHG1*01 (100%)G1m17,1 (CH1 K120 (218) (122-219), hinge 1-15(220-234), CH2 (235-344), CH3
Common Name English
Immunoglobulin G1, anti-(human tumor necrosis factor) (human monoclonal D2E7 heavy chain), complex with human monoclonal D2E7 light chain, dimer, 214??,214???,224,224?-tetrakis(thioether) with N-(2-mercaptoacetyl)glycyl-N-[3-[[4-[(R)-[[(11?,16?)-11-hydro
Common Name English
ABBV154
Code English
Code System Code Type Description
SMS_ID
300000014560
Created by admin on Wed Apr 02 03:16:37 GMT 2025 , Edited by admin on Wed Apr 02 03:16:37 GMT 2025
PRIMARY
USAN
LM-233
Created by admin on Wed Apr 02 03:16:37 GMT 2025 , Edited by admin on Wed Apr 02 03:16:37 GMT 2025
PRIMARY
NCI_THESAURUS
C190447
Created by admin on Wed Apr 02 03:16:37 GMT 2025 , Edited by admin on Wed Apr 02 03:16:37 GMT 2025
PRIMARY
INN
11661
Created by admin on Wed Apr 02 03:16:37 GMT 2025 , Edited by admin on Wed Apr 02 03:16:37 GMT 2025
PRIMARY
FDA UNII
FWC6IWT3EH
Created by admin on Wed Apr 02 03:16:37 GMT 2025 , Edited by admin on Wed Apr 02 03:16:37 GMT 2025
PRIMARY
CAS
2402772-93-2
Created by admin on Wed Apr 02 03:16:37 GMT 2025 , Edited by admin on Wed Apr 02 03:16:37 GMT 2025
PRIMARY
From To
1_22 1_96
1_148 1_204
1_224 3_214
1_230 2_230
1_233 2_233
1_265 1_325
1_371 1_429
2_22 2_96
2_148 2_204
2_224 4_214
2_265 2_325
2_371 2_429
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
ADALIMUMAB
PARENT -> CONJUGATE
GLUCOCORTICOID RECEPTOR
TARGET->MODULATOR
TUMOR NECROSIS FACTOR-.ALPHA. HUMAN (PLASMA DERIVED, SOLUBLE FORM)
TARGET -> INHIBITOR

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION UNKNOWN Amount: Cysteinyl fosimdesonide VXP6125PI2
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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