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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 09:25:51 UTC 2023
Edited
by admin
on Sat Dec 16 09:25:51 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
4TVX2I407K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TUMOR NECROSIS FACTOR-.ALPHA. HUMAN (PLASMA DERIVED, SOLUBLE FORM)
Common Name English
TNF-.ALPHA.
Common Name English
TUMOR NECROSIS FACTOR-.ALPHA. HUMAN (SOLUBLE FORM)
Common Name English
TUMOR NECROSIS FACTOR-.ALPHA. (SOLUBLE FORM)
Common Name English
Tumor necrosis factor alpha [WHO-DD]
Common Name English
TUMOR NECROSIS FACTOR .ALPHA. HUMAN (SOLUBLE FORM)
Common Name English
CACHECTIN
Common Name English
TUMOR NECROSIS FACTOR-ALPHA
Common Name English
TUMOR NECROSIS FACTOR-.ALPHA.
Common Name English
Code System Code Type Description
CAS
308079-78-9
Created by admin on Sat Dec 16 09:25:52 UTC 2023 , Edited by admin on Sat Dec 16 09:25:52 UTC 2023
PRIMARY
EPA CompTox
DTXSID4040634
Created by admin on Sat Dec 16 09:25:52 UTC 2023 , Edited by admin on Sat Dec 16 09:25:52 UTC 2023
PRIMARY
MESH
D014409
Created by admin on Sat Dec 16 09:25:52 UTC 2023 , Edited by admin on Sat Dec 16 09:25:52 UTC 2023
PRIMARY
PUBCHEM
161495
Created by admin on Sat Dec 16 09:25:52 UTC 2023 , Edited by admin on Sat Dec 16 09:25:52 UTC 2023
PRIMARY
FDA UNII
4TVX2I407K
Created by admin on Sat Dec 16 09:25:52 UTC 2023 , Edited by admin on Sat Dec 16 09:25:52 UTC 2023
PRIMARY
EVMPD
SUB75902
Created by admin on Sat Dec 16 09:25:52 UTC 2023 , Edited by admin on Sat Dec 16 09:25:52 UTC 2023
PRIMARY
From To
3_69 3_101
2_69 2_101
1_69 1_101
Glycosylation Type HUMAN
Glycosylation Link Type Site
O 1_3
O 2_3
O 3_3
Related Record Type Details
Structure of BMS-561392
INHIBITOR -> TARGET
SELECTIVE
ANTI-TNF-.ALPHA (OVINE, FAB)
INHIBITOR -> TARGET
Structure of ROFLUMILAST N-OXIDE
INHIBITOR OF RELEASE->TARGET
In human PBMCs
IC50
ADALIMUMAB
INHIBITOR -> TARGET
BINDING
TANFANERCEPT
INHIBITOR -> TARGET
Structure of ELSIBUCOL
INHIBITOR OF RELEASE->TARGET
REMTOLUMAB
INHIBITOR -> TARGET
OZORALIZUMAB
INHIBITOR -> TARGET
Adalimumab Fosimdesonide
INHIBITOR -> TARGET
Structure of CEPHARANTHINE
INHIBITOR -> TARGET
BINDING
Structure of ISOINDOLIN-1,3-DITHIONE
INHIBITOR OF EXPRESSION->TARGET
Directed against TNF.alpha. mRNA
ETANERCEPT
INHIBITOR -> TARGET
BINDING
Structure of ACETYLCYSTEINE
INHIBITOR -> TARGET
N-acetylcysteine inhibited the TNF-α-stimulated production of cytokines and chemokines
CERTOLIZUMAB PEGOL
INHIBITOR -> TARGET
BINDING
Licaminlimab
INHIBITOR -> TARGET
AFAMITRESGENE AUTOLEUCEL
T-CELLS->EXPRESSED PROTEIN
upon activation
EDI-200
INHIBITOR -> TARGET
Structure of VADIMEZAN
ACTIVATOR -> TARGET
NERELIMOMAB
INHIBITOR -> TARGET
Structure of DELMITIDE
INHIBITOR OF EXPRESSION->TARGET
CERTOLIZUMAB
INHIBITOR -> TARGET
Structure of LEO-39652
INHIBITOR OF RELEASE->TARGET
IC50
Structure of THALIDOMIDE
INHIBITOR -> TARGET
BINDING
PLACULUMAB
INHIBITOR -> TARGET
Structure of APREMILAST
INHIBITOR -> TARGET
INHIBITS PDE4 AND INCREASES cAMP CONCENTRATION
INDIRECT
AFELIMOMAB
INHIBITOR -> TARGET
Structure of EDRATIDE
INHIBITOR OF EXPRESSION->TARGET
Structure of CAMOBUCOL
INHIBITOR -> TARGET
Structure of AN-0128
INHIBITOR -> TARGET
Inhibition of LPS-induced TNF-α release from human monocytes
INFLIXIMAB
INHIBITOR -> TARGET
BINDING
Structure of 2-(4-(4-CHLOROPHENOXY)-3,5-DIMETHYL-1H-PYRAZOL-1-YL)-4-(2-PYRIDINYL)PYRIMIDINE
MODULATOR->TARGET
GOLIMUMAB
INHIBITOR -> TARGET
Structure of LENALIDOMIDE
INHIBITOR -> TARGET
BINDING
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:CALCULATED CHEMICAL
NIH
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