Details
Stereochemistry | RACEMIC |
Molecular Formula | C17H25N3O |
Molecular Weight | 287.3999 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC(C1=NOC(CCN(CC)CC)=N1)C2=CC=CC=C2
InChI
InChIKey=OLTAWOVKGWWERU-UHFFFAOYSA-N
InChI=1S/C17H25N3O/c1-4-15(14-10-8-7-9-11-14)17-18-16(21-19-17)12-13-20(5-2)6-3/h7-11,15H,4-6,12-13H2,1-3H3
Molecular Formula | C17H25N3O |
Molecular Weight | 287.3999 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/7194677Curator's Comment: description was created based on several sources, including
http://www.ncbi.nlm.nih.gov/pubmed/5314719
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7194677
Curator's Comment: description was created based on several sources, including
http://www.ncbi.nlm.nih.gov/pubmed/5314719
Proxazole or 3-alpha-Phenyl-propyl-5-beta-diethylaminoethyl-1,2,3-oxadiazole is a drug used for functional gastrointestinal disorders. It’s an unusual drug because it possesses both anti-inflammatory and antispasmodic properties and because each of these two properties has some uncommon features. The antiinflammatory action takes place mostly against edematous responses and is devoid of ulcerogenic effects which are instead produced by most anti-inflammatory drugs; moreover proxazole prevents indomethacin-induced ulcers without exerting any anti-secretory effect. The antispasmodic activity results in a specific inhibition of smooth muscle spasm, both at the vascular and at the intestinal level, without significant interferences with the physiologic activity of that tissue.
Originator
Sources: http://www.ncbi.nlm.nih.gov/pubmed/19203813
Curator's Comment: 1989
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7194677
oral: 400 mg proxazole (5.2--6.5 mg/kg/day)
Route of Administration:
Other
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:13:18 GMT 2023
by
admin
on
Fri Dec 15 16:13:18 GMT 2023
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Record UNII |
FD72T13M0K
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29698
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WHO-VATC |
QA03AX07
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WHO-ATC |
A03AX07
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Code System | Code | Type | Description | ||
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m9282
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PRIMARY | Merck Index | ||
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2321
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100000080838
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SUB10146MIG
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CHEMBL2106997
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PRIMARY | |||
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DTXSID90859261
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PRIMARY | |||
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PROXAZOLE
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8590
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PRIMARY | |||
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FD72T13M0K
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PRIMARY | |||
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C74176
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PRIMARY | |||
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DB13819
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1797
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31363-08-3
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5696-09-3
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C005583
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PRIMARY |
Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
Related Record | Type | Details | ||
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ACTIVE MOIETY |