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Details

Stereochemistry RACEMIC
Molecular Formula C17H25N3O.C6H8O7
Molecular Weight 479.5234
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROXAZOLE CITRATE

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCC(C1=NOC(CCN(CC)CC)=N1)C2=CC=CC=C2

InChI

InChIKey=WFAULHLDTDDABL-UHFFFAOYSA-N
InChI=1S/C17H25N3O.C6H8O7/c1-4-15(14-10-8-7-9-11-14)17-18-16(21-19-17)12-13-20(5-2)6-3;7-3(8)1-6(13,5(11)12)2-4(9)10/h7-11,15H,4-6,12-13H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Molecular Formula C17H25N3O
Molecular Weight 287.3999
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Molecular Formula C6H8O7
Molecular Weight 192.1235
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Proxazole Citrate is a spasmolytic papaverine-like agent used for functional gastrointestinal disorders in veterinary and acute renal insufficiency. In animal models, Proxazole has antitussive, antispasmodic, analgesic, anti-inflammatory, and antipyretic activities. Proxazole has veterinary uses against gastritis, infective and non-infective gastro-enteritis, urethritis, cystitis and spastic states with an inflammatory component of the smooth muscles of the digestive and genito-urinary systems. Proxazole is excreted both in feces and urine mainly as inactive metabolites.

Approval Year

PubMed

PubMed

TitleDatePubMed
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:24:30 GMT 2023
Edited
by admin
on Fri Dec 15 15:24:30 GMT 2023
Record UNII
YR02IKM54O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROXAZOLE CITRATE
JAN   MI   USAN   WHO-DD  
USAN  
Official Name English
Proxazole citrate [WHO-DD]
Common Name English
AF-634
Code English
PROXAZOLE CITRATE [USAN]
Common Name English
NSC-303872
Code English
PIRECIN
Brand Name English
PROPAXOLINE
Common Name English
1,2,4-OXADIAZOLE, 5-(2-(DIETHYLAMINO)ETHYL)-3-(.ALPHA.-ETHYLBENZYL)-, CITRATE (1:1)
Systematic Name English
PROXAZOLE CITRATE [JAN]
Common Name English
PROXAZOL CITRATE
Common Name English
SOLACIL
Brand Name English
1,2,4-OXADIAZOLE-5-ETHANAMINE, N,N-DIETHYL-3-(1-PHENYLPROPYL)-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)
Systematic Name English
3.ALPHA.-PHENYLPROPYL-5.BETA.-DIETHYLAMINOETHYL-1,2,4-OXADIAZOL CITRATE
Common Name English
PROXAZOLE CITRATE [MI]
Common Name English
3-.ALPHA.-PHENYLPROPYL-5-(.BETA.-DIETHYLAMINOETHYL)-1,2,4-OXADIAZOLE CITRATE
Common Name English
TONESS
Brand Name English
FLOU
Common Name English
PROPAXOLIN
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29698
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
Code System Code Type Description
FDA UNII
YR02IKM54O
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
ECHA (EC/EINECS)
205-059-8
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
MERCK INDEX
m9282
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY Merck Index
CAS
31363-11-8
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
SUPERSEDED
ChEMBL
CHEMBL2106997
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
CAS
19248-55-6
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
NON-SPECIFIC STOICHIOMETRY
PUBCHEM
8589
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
CAS
132-35-4
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
NSC
303872
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
EPA CompTox
DTXSID5048760
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
NCI_THESAURUS
C152111
Created by admin on Fri Dec 15 15:24:30 GMT 2023 , Edited by admin on Fri Dec 15 15:24:30 GMT 2023
PRIMARY
Related Record Type Details
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PARENT -> SALT/SOLVATE