PROXAZOLE CITRATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H25N3O.C6H8O7
Molecular Weight	479.5234
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCC(C1=NOC(CCN(CC)CC)=N1)C2=CC=CC=C2

InChI

InChIKey=WFAULHLDTDDABL-UHFFFAOYSA-N

InChI=1S/C17H25N3O.C6H8O7/c1-4-15(14-10-8-7-9-11-14)17-18-16(21-19-17)12-13-20(5-2)6-3;7-3(8)1-6(13,5(11)12)2-4(9)10/h7-11,15H,4-6,12-13H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Molecular Formula	C17H25N3O
Molecular Weight	287.3999
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	C6H8O7
Molecular Weight	192.1235
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7194677 | https://www.ncbi.nlm.nih.gov/pubmed/7619896 | https://www.ncbi.nlm.nih.gov/pubmed/7016648

Proxazole Citrate is a spasmolytic papaverine-like agent used for functional gastrointestinal disorders in veterinary and acute renal insufficiency. In animal models, Proxazole has antitussive, antispasmodic, analgesic, anti-inflammatory, and antipyretic activities. Proxazole has veterinary uses against gastritis, infective and non-infective gastro-enteritis, urethritis, cystitis and spastic states with an inflammatory component of the smooth muscles of the digestive and genito-urinary systems. Proxazole is excreted both in feces and urine mainly as inactive metabolites.

Approval Year

PubMed

Title	Date	PubMed
GC-ITD detection and quantitative analysis of proxazole in cows' plasma and milk.	1995 Mar	7619896

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:24:30 UTC 2023` Edited by `admin` on `Fri Dec 15 15:24:30 UTC 2023`
Record UNII	YR02IKM54O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROXAZOLE CITRATE

Official Name

English

Proxazole citrate [WHO-DD]

Common Name

English

AF-634

Code

English

PROXAZOLE CITRATE [USAN]

Common Name

English

NSC-303872

Code

English

PIRECIN

Brand Name

English

PROPAXOLINE

Common Name

English

1,2,4-OXADIAZOLE, 5-(2-(DIETHYLAMINO)ETHYL)-3-(.ALPHA.-ETHYLBENZYL)-, CITRATE (1:1)

Systematic Name

English

PROXAZOLE CITRATE [JAN]

Common Name

English

PROXAZOL CITRATE

Common Name

English

SOLACIL

Brand Name

English

1,2,4-OXADIAZOLE-5-ETHANAMINE, N,N-DIETHYL-3-(1-PHENYLPROPYL)-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)

Systematic Name

English

3.ALPHA.-PHENYLPROPYL-5.BETA.-DIETHYLAMINOETHYL-1,2,4-OXADIAZOL CITRATE

Common Name

English

PROXAZOLE CITRATE [MI]

Common Name

English

3-.ALPHA.-PHENYLPROPYL-5-(.BETA.-DIETHYLAMINOETHYL)-1,2,4-OXADIAZOLE CITRATE

Common Name

English

TONESS

Brand Name

English

FLOU

Common Name

English

PROPAXOLIN

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29698