IOCETAMIC ACID

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H13I3N2O3
Molecular Weight	613.9566
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CC(CN(C(C)=O)C1=C(I)C(N)=C(I)C=C1I)C(O)=O

InChI

InChIKey=GSVQIUGOUKJHRC-UHFFFAOYSA-N

InChI=1S/C12H13I3N2O3/c1-5(12(19)20)4-17(6(2)18)11-8(14)3-7(13)10(16)9(11)15/h3,5H,4,16H2,1-2H3,(H,19,20)

HIDE SMILES / InChI

Molecular Formula	C12H13I3N2O3
Molecular Weight	613.9566
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description

Iocetamic acid is a medical diagnostic aid. It is a contrast agent used to enhance structures or fluids during X-ray imaging.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Gallbladder disease 13	Diagnostic		Approved 8,429	CHOLEBRINE

T_1/2

Value	Dose	Co-administered	Analyte	Population
20 h	750 mg single, oral		IOCETAMIC ACID plasma	Homo sapiens

F_unbound

Value	Dose	Co-administered	Analyte	Population
1%	750 mg single, oral		IOCETAMIC ACID plasma	Homo sapiens

Doses

Show entries

Dose	Population	Adverse events
3 g 2 times / day multiple, oral Highest studied dose	unhealthy, adult	Other AEs: Vomiting, Nausea...
3 g 2 times / day multiple, oral Highest studied dose	unhealthy, adult	Other AEs: Ankle swelling, Feeling of warmth...
4.5 g single, oral Highest studied dose	unhealthy	Disc. AE: Skin infection...
3 g single, oral	unhealthy	Disc. AE: Skin infection...

Showing 1 to 4 of 4 entries

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AEs

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AE	Significance	Dose	Population
Skin rash	1 patient	3 g 2 times / day multiple, oral Highest studied dose	unhealthy, adult
Vomiting	1 patient	3 g 2 times / day multiple, oral Highest studied dose	unhealthy, adult
Watery diarrhoea	1 patient	3 g 2 times / day multiple, oral Highest studied dose	unhealthy, adult
Abdominal pain	12 patients	3 g 2 times / day multiple, oral Highest studied dose	unhealthy, adult
Nausea	14 patients	3 g 2 times / day multiple, oral Highest studied dose	unhealthy, adult

Showing 1 to 5 of 24 entries

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Sourcing

Sourcing

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Vendor/Aggregator	ID	URL
001 Chemical	DY528434	https://www.001chemical.com/chem/16034-77-8
ABI Chem	AC1L1DNS
Alfa Chemistry	16034-77-8
Ambinter	Amb22489954	http://www.ambinter.com/reference/22489954
BLD Pharm	BD134734	http://www.bldpharm.com/products/16034-77-8.html

Showing 1 to 5 of 17 entries

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Patents

Patents

Sample Use Guides

In Vivo Use Guide

Administer 750 mg on the examination day.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical
Record UNII	FA675Q0E3E
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

IOCETAMIC ACID

Official Name

English

MP-620

Code

English

N-Acetyl-N-(3-amino-2,4,6-triiodophenyl)-2-methyl-β-alanine

Systematic Name

English

IOCETAMIC ACID [HSDB]

Common Name

English

CHOLEBRINE

Brand Name

English

Showing 1 to 5 of 13 entries

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Classification Tree

Code System

Code

Contrast Agent

NCI_THESAURUS

C28500

Watersoluble, hepatotropic X-ray contrast media

WHO-VATC

QV08AC07

Watersoluble, hepatotropic X-ray contrast media

WHO-ATC

V08AC07

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Code System

Code

Type

Description

MERCK INDEX

m6324

PRIMARY

Merck Index

ECHA (EC/EINECS)

240-173-1

PRIMARY

FDA UNII

FA675Q0E3E

PRIMARY

DRUG BANK

DB09403

PRIMARY

CAS

16034-77-8

PRIMARY

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Related Record

Type

Details


					FA675Q0E3E

IOCETAMIC ACID

ACTIVE MOIETY

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SMILES

InChI

Originator

Approval Year

Conditions

T1/2

Funbound

Doses

AEs

Sourcing

Patents

Sample Use Guides

T_1/2

F_unbound