VILOBELIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:16:59 GMT 2023` Edited by `admin` on `Sat Dec 16 14:16:59 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	F5T0RF9ZJA
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VILOBELIMAB

Official Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN COMPLEMENT C5A) (HUMAN-MUS MUSCULUS MONOCLONAL IFX-1 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IFX-1 .KAPPA.-CHAIN, DIMER

Systematic Name

English

CACP29

Code

English

vilobelimab [INN]

Common Name

English

Vilobelimab [WHO-DD]

Common Name

English

IFX-1

Code

English

VILOBELIMAB [USAN]

Common Name

English

CACP 29

Code

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS C5 (COMPLEMENT 5) ANAPHYLATOXIN (C5A, C5 PR678-751)), CHIMERIC MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN CHIMERIC (1-446) (VH (MUS MUSCULUS IGHV1-61*01 (81.6%)-(IGHD)-IGHJ3*01 (92.9%)/HOMO SAPIENS IGHV1-46*01 (62.2

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

884822

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

Code System Code Type Description

USAN

HI-123

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

PRIMARY

SMS_ID

300000021741

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

PRIMARY

FDA UNII

F5T0RF9ZJA

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

PRIMARY

INN

11304

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

PRIMARY

CAS

2250440-41-4

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

PRIMARY

CAS

2161337-20-6

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

SUPERSEDED

NCI_THESAURUS

C172643

Created by admin on Sat Dec 16 14:16:59 GMT 2023 , Edited by admin on Sat Dec 16 14:16:59 GMT 2023

PRIMARY

From	To
1_23	1_92
2_23	2_92
3_22	3_96
3_146	3_202
3_260	3_320
3_366	3_424
4_22	4_96
4_146	4_202
4_260	4_320
4_366	4_424
3_225	4_225
3_228	4_228
1_138	1_198
1_218	3_133
2_138	2_198
2_218	4_133

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	3_296
N	4_296

Related Record Type Details


					X0HO3HK1PW

COMPLEMENT C5 ALPHA CHAIN

TARGET -> INHIBITOR

Related Record Type Details


					F5T0RF9ZJA

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL